Dexpin Tablet (Dexibuprofen D.C.)

Adult dose

Adults: Administer 300 mg of dexibuprofen per dose orally 2–4 times daily. Do not exceed 1,200 mg of dexibuprofen per day.

Those who regularly consume more than three glasses of alcohol per day should consult with a doctor or pharmacist before taking this medication, as there is a risk of gastrointestinal bleeding. This medication may have effects on the cardiovascular system; therefore, individuals at risk for heart disease or stroke should be particularly cautious and monitor for symptoms related to the cardiovascular system. Serious issues such as gastrointestinal bleeding, ulcers, and perforation may occur, so it is advisable not to take this medication if there is a history of gastrointestinal disease or if symptoms are present. Those with heart disease, high blood pressure, or compromised kidney or liver function should consult a healthcare professional before taking this medication. Caution should be exercised to avoid concurrent use with other non-steroidal anti-inflammatory drugs (NSAIDs), aspirin, or certain medications as this may increase the risk of side effects. Dizziness or drowsiness may occur while taking this medication, so care should be taken when driving or operating machinery. It is safer not to take this medication during pregnancy, particularly after the sixth month, as it may harm the fetus. If skin rash, respiratory distress, or severe gastrointestinal symptoms occur while taking this medication, discontinue use immediately and consult a healthcare professional. Regular blood tests and assessments of liver and kidney function are important if taking this medication for an extended period. This medication should be administered to children 6 years or older at the minimum necessary dose with caution, as safety has not been established for children under 6 years of age. If abnormal symptoms appear after taking the medication, consult a healthcare professional immediately and bring the attached document if any suspicious symptoms are noted. Store this medication out of reach of children, away from direct sunlight, and in a cool, dry place.

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcers, perforation, dyspepsia, abdominal distension, heartburn, pain in the upper abdomen, diarrhea, constipation, loss of appetite, nausea, vomiting, abdominal pain, discomfort in the upper abdomen, esophagitis, esophageal stricture, aggravated diverticulitis, nonspecific hemorrhagic colitis, ulcerative colitis, Crohn's disease, peptic ulcer, gastrointestinal bleeding, perforation, blood in stool, gastritis, pancreatitis, thirst, stomatitis, erythema multiforme, systemic lupus erythematosus, hair loss, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, eosinophilia, drug rash with systemic syndrome, acute generalized pustular psoriasis, rash, urticaria, itching, purpura, asthma attacks, eczema, anaphylactic reaction, photosensitivity reaction, jaundice, elevated ALT, elevated AST, elevated ALP, abnormal liver function, hepatitis, rhinitis, bronchospasm, acute pneumonia, neglect, bone marrow infiltration, visual impairment, hearing loss, tinnitus, taste disturbance, fatigue, drowsiness, headache, dizziness, anxiety, restlessness, confusion, depression, aseptic meningitis, mental disturbances, agitation, excitement, spatial disorientation, reversible toxic amnesia, hypotension, hypertension, palpitations, acute renal failure, oliguria, hematuria, increased urinary protein, elevated BUN, elevated serum creatinine, hyperkalemia, decreased urine output, generalized edema, shortness of breath, lethargy, renal papillary necrosis, nephrotic syndrome, interstitial nephritis, peripheral edema, acute pulmonary edema, fluid retention, Kohnis syndrome, decreased reproductive capacity in women, periorbital edema, fatigue, fever, nosebleeds, exacerbation of inflammation, crying, facial edema, dyspepsia, pruritus, anaphylactic shock, rash, diarrhea, vomiting

Drug interactions

This medication should not be taken with aspirin, other non-steroidal anti-inflammatory drugs, or high doses of methotrexate. Additionally, avoid concurrent use with corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors or angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants, baclofen, immunosuppressants, thrombolytics, ticlopidine, antiplatelet agents, or potassium levels.

This medication must be stored in a tightly closed container to protect it from air and moisture. The storage temperature should be maintained between 1 degree and 30 degrees in a cool environment.

Appearance

White oval film-coated tablet

Package unit

300 tablets/bottle, 30 tablets/bottle