InnoEn Hydrochloride Dopamine Premix 320 mg Injection

Adult administration

Administer intravenously at 2-5 mcg/min per kg of body weight as dopamine hydrochloride. In severe cases, it may be increased to 5-10 mcg/min up to 20-50 mcg/min and administered intravenously. Adjust according to age and symptoms.

This medication contains dopamine hydrochloride, and patients who have taken monoamine oxidase inhibitors before should reduce the dosage. There is insufficient research on the safety and appropriate dosage for children, so it is advisable not to use it in pediatric patients. The efficacy may decrease if mixed with alkaline solutions, thus it should not be mixed with alkaline diluents other than 5% dextrose injection. It should not be administered to patients with specific diseases such as heart disease, thyroid disease, and glaucoma, and caution is required for patients allergic to starch. Patients with peripheral vascular disorders or allergies to sulfites must consult with healthcare professionals before administration. If the drug leaks outside of the blood vessels, tissue necrosis may occur; therefore, it is safe to carefully monitor the infusion site and administer it via large veins. Various side effects such as cardiac arrhythmias, blood pressure changes, gastrointestinal symptoms, skin changes, headaches, and anxiety may occur, so it is important to report any abnormal symptoms immediately. Blood pressure, heart rate, and urine output should be closely monitored during administration, and dosage adjustments or cessation of administration may be necessary depending on the condition. During pregnancy, the risks and benefits to the fetus should be carefully considered, and during breastfeeding, it is advisable to avoid administration or discontinue breastfeeding if possible. Elderly patients should start at low doses considering their liver, kidney, and heart function decrease. Overdosage may lead to symptoms such as increased blood pressure; in such cases, the infusion rate should be slowed or temporarily halted, and specialized treatment should be sought as necessary. This medication may interact with other drugs, so it is essential to inform healthcare professionals if taking other medications.

Serious side effects

• Dyspnea
• Asthma attack
• Hypokalemia
• Ventricular arrhythmia
• Increased blood pressure
• Tissue necrosis and scab formation due to extravascular leakage
• Severe allergic reactions (sulfite anaphylaxis)
• Pulmonary edema
• Severe hypotension
• Severe hypertension

Mild side effects

• Ventricular premature contractions, atrial fibrillation, ventricular tachycardia
• Nausea, vomiting, abdominal distension, abdominal pain
• Piloerection
• Headache, anxiety, phlebitis, necrosis at the injection site, and hirsutism
• Hypotension, hypertension, palpitations, angina, vascular constriction, bradycardia, hypernitrogenemia

This medication should be stored in a sealed container to prevent air and moisture from entering, and it is important to maintain a storage temperature at room temperature, avoiding extreme heat or cold. Proper storage will help maintain the medication's efficacy for a long time.

Appearance

A colorless or pale yellow transparent injection solution filled in a colorless transparent plastic container for infusion.

Package unit

250 milliliters / box