Lofepram Injection 2mL (Diclofenac Sodium)

Adult dosage

(Oral) As diclofenac sodium, the initial dose is 100-150mg per day and for maintenance or long-term therapy, 75-100mg per day in 2-3 divided doses. (Injection) As diclofenac sodium, administer 75mg (1 ampoule) intramuscularly deep into one side of the upper buttock once daily. In severe cases, 75mg may be given twice daily, alternating injections in both buttocks.

Children's dosage

Administer 0.5-3mg per kg of body weight per day in 2-3 divided doses. Adjust according to age, condition, and symptoms.

This medication should be discussed with a doctor or pharmacist before taking by anyone who drinks more than three glasses of alcohol regularly. Combining it with alcohol may increase the risk of gastrointestinal bleeding. This drug may increase the risk of cardiovascular disease, so those with a history of heart disease or stroke or risk factors should be particularly cautious. Symptoms of cardiovascular issues should be carefully monitored during use, and if symptoms occur, medical consultation should be sought immediately. This medication can cause serious problems such as gastrointestinal bleeding, ulcers, or perforation, so elderly patients or those with a history of gastrointestinal disease should take special care when using it. If signs of gastrointestinal bleeding appear during treatment, use should be stopped immediately and a doctor consulted. Those with hypersensitivity to this medication or a history of asthma, urticaria, or allergic reactions should avoid taking it, and if any allergy symptoms occur, use should be stopped immediately. In the case of an injectable formulation, care should be taken when cutting the container to avoid glass shards, especially when used by children or the elderly. This drug should not be administered to individuals with certain conditions, such as peptic ulcer, severe blood disorders, liver dysfunction, kidney dysfunction, hypertension, or heart failure. During use, the minimum effective dose should be used for the shortest duration possible, and regular blood tests and liver and kidney function tests should be performed during long-term use. This medication may increase the risk of side effects when taken with other non-steroidal anti-inflammatory drugs, so concomitant use should be avoided. It may be harmful to the fetus during pregnancy, especially in late pregnancy, so pregnant women should avoid taking this medication, and breastfeeding mothers are advised to either discontinue nursing or stop the medication. Children and the elderly should be especially cautious when taking this medication, and in the case of overdose, immediate medical assistance should be sought.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough + fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Rash
• itching
• increased blood pressure
• decreased blood pressure
• palpitations
• tachycardia
• frequency of urination
• nocturia
• erectile dysfunction
• vaginal bleeding

This medication may be sensitive to light, so it should be stored in a light-resistant sealed container. Additionally, it is advisable to store it at room temperature rather than in excessively hot or cold environments.

Appearance

A colorless or pale yellow transparent liquid in a brown transparent ampoule

Package unit

2mL/ampoule × 50