Medication info

Dipeamine 2 mL (Diclofenac β-Dimethylaminoethanol)

Prescription medicationSolutionExpired
Ingredient · strength
Diclofenac Beta-Dimethylaminoethanol›45mg / 1mL
Manufacturer / importer
동광제약(주)
Appearance
A brown ampoule containing a colorless to pale yellow transparent solution
Packaging
50 ampoules (2 mL/ampoule × 50)
Approval status
Expired

MFDS item code 200100129 · Notified 2001.04.19

This product's status changed to Expired on 2024.04.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of inflammation and pain in conditions such as rheumatoid arthritis and osteoarthritis
Who uses it
Adults
Adult dosage
Administer Diclofenac β-Dimethylaminoethanol as a deep intramuscular injection of 90 mg once daily into the upper outer quadrant of the buttock. For severe cases, it may be administered in doses of 90 mg twice a day, alternating between both buttocks. After initial treatment, it should be converted to oral tablets or rectal formulations. Adjust the dosage as appropriate based on age, condition, and symptoms. To minimize cardiovascular adverse reactions, use the minimum effective dose for the shortest time possible.

Ingredients

Manufacturer
동광제약(주)

Efficacy & effects

Relief of inflammation and pain in conditions such as rheumatoid arthritis and osteoarthritis

  • Rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • post-traumatic inflammation
  • post-surgical inflammation
  • pain
  • acute gout
  • renal colic
  • hepatic colic
View approved original text

This medicine is used for chronic inflammatory joint diseases such as rheumatoid arthritis, osteoarthritis (degenerative joint disease), and ankylosing spondylitis. It is also effective in relieving inflammation and pain following trauma or surgery. It is used for acute gout and renal and hepatic colic as well. Thus, it is widely used for the treatment of various inflammation and pain-related conditions.

Dosage and Administration

Adult dosage

Administer Diclofenac β-Dimethylaminoethanol as a deep intramuscular injection of 90 mg once daily into the upper outer quadrant of the buttock. For severe cases, it may be administered in doses of 90 mg twice a day, alternating between both buttocks. After initial treatment, it should be converted to oral tablets or rectal formulations. Adjust the dosage as appropriate based on age, condition, and symptoms. To minimize cardiovascular adverse reactions, use the minimum effective dose for the shortest time possible.

Precautions

This medicine should be consulted with a doctor or pharmacist before use by individuals who regularly consume three glasses or more of alcohol daily. This is because taking this medicine while heavily drinking can lead to gastrointestinal bleeding. This medicine may pose risks to the heart and blood vessels. Particularly, those with existing cardiovascular diseases or risk factors should be more cautious, and symptoms should be closely monitored in case severe issues like myocardial infarction or stroke occur. This medicine can also cause gastrointestinal issues. Serious adverse reactions such as gastrointestinal bleeding, ulcers, or perforation may occur, with the risk being greater in the elderly. Those with previous gastrointestinal issues need to be especially careful, and any symptoms of gastrointestinal bleeding require immediate medical attention. Individuals allergic to this medicine or with a history of allergic reactions such as asthma or urticaria should not take it. Severe allergic reactions can potentially lead to a myocardial infarction, so caution is necessary. As this medication is injectable, care should be taken to avoid glass particles when opening the ampoule, especially for children and the elderly. Patients with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, hypertension, or heart failure should not take this medication. Patients who have had allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs should also avoid it. This medicine should be administered cautiously to patients with a history of peptic ulcers, liver, kidney, or heart diseases, those with hypertension or asthma, the elderly, and children. While taking, rare side effects such as shock, gastrointestinal bleeding, blood disorders, skin rashes, altered liver function, decreased kidney function, allergic reactions, headaches, dizziness, etc. may occur. If these symptoms appear, immediate consultation with a doctor is necessary. This medicine should be taken for the shortest duration possible and at the minimum effective dose. Long-term use should involve regular blood tests and checks of liver and kidney function. Taking this medicine in combination with other non-steroidal anti-inflammatory drugs may increase the risk of side effects, so they should not be taken together. It may also interact with certain medications, so any other medications being taken should be disclosed to a doctor or pharmacist. This medicine should not be used during pregnancy, especially in the late stages, and care should be taken after the 20th week of pregnancy as it may affect fetal kidney function. While breastfeeding, this medicine may pass into breast milk and potentially cause adverse reactions in the infant, so consideration should be given to stopping breastfeeding or discontinuing the medication. The elderly and children should be particularly cautious of side effects and take the minimum dose of this medication.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues

Mild side effects

  • Loss of appetite
  • nausea
  • vomiting
  • abdominal pain
  • diarrhea
  • stomatitis
  • thirst
  • constipation
  • headache
  • drowsiness
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  • dizziness
  • insomnia
  • irritability
  • tingling
  • confusion
  • hallucinations
  • seizures
  • blurred vision
  • tinnitus
  • increased blood pressure
  • decreased blood pressure
  • palpitations
  • tachycardia
  • general malaise
  • sweating
  • hair loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that prevents light exposure. Additionally, it is important to maintain a temperature between 1 degrees and 30 degrees Celsius while storing it. This way, the effectiveness of the medication can be preserved for a longer period.

Appearance and packaging

Appearance

A brown ampoule containing a colorless to pale yellow transparent solution

Package unit

50 ampoules (2 mL/ampoule × 50)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.