Pariet 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Administer 10 mg of rabeprazole sodium orally once daily. Depending on symptoms, 20 mg can be administered orally once daily. For gastric ulcers, treatment can continue up to 8 weeks; for duodenal ulcers, up to 6 weeks. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If not resolved after 8 weeks of treatment, an additional 8-week course may be considered.

This medication should not be used in patients with a history of allergies or hypersensitivity to certain ingredients or benzimidazoles. Patients allergic to penicillin-based or macrolide antibiotics should also be cautious when using this medication with antibiotics. Particularly, it should not be used in patients taking specific heart medications or those treated with atazanavir or rilpivirine, or in pregnant or lactating women. Patients with poor liver function or elderly patients, as well as those with a history of drug allergies, should use this medication cautiously. This medication can rarely cause various side effects such as skin rash, itching, blood abnormalities, liver function abnormalities, and cardiovascular and gastrointestinal issues, so if any unusual symptoms occur, consult a doctor immediately. Regular blood tests and liver function tests are important during prolonged use, especially if used for more than one year. This medication significantly inhibits gastric acid secretion, which may slightly increase the risk of bacterial infections in the stomach; if diarrhea persists, inform a doctor. Caution is needed when driving or operating machinery due to the possibility of drowsiness. This medication may interact with other drugs, so inform healthcare providers of any concurrent medications, and dosage adjustments or monitoring may be necessary. It should not be taken during pregnancy or lactation, especially by pregnant women, as it may affect the fetus. Elderly patients are at higher risk of side effects due to decreased liver function, so they should discontinue use and consult a healthcare provider if symptoms arise. This medication must be swallowed whole and not chewed or crushed, and should be stored out of reach of children. In cases of overdose, there is no specific antidote, and treatment should be provided based on symptoms according to healthcare providers' instructions. Long-term use of this medication may increase the risk of gastric polyps, so the lowest effective dose and shortest duration of use are recommended. Additionally, if symptoms similar to erythema multiforme or systemic lupus erythematosus occur during use, the medication should be discontinued immediately and evaluated by a specialist.

Serious side effects

• Urticaria
• severe swelling (edema)
• chest tightness
• difficulty breathing
• severe rash with fever
• blistering
• skin peeling
• pain in oral/eye mucosa
• liver abnormalities (jaundice)
• extreme lethargy

Mild side effects

• Rash
• itching
• erythrocytopenia
• leukopenia
• leukocytosis
• eosinophilia
• neutrophilia
• lymphocytopenia
• anemia
• petechiae

This medication can be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This ensures the medication's effectiveness and safety over time.

Appearance

Pale yellow round film-coated tablet

Package unit

56 tablets (14 tablets x 4 PTP) / box