Sadenin Tablet (S-Adenosyl-L-Methionine Sulfate Tosylate)

Adult dose

1. Depression ○ Adults - Initial treatment: Administer 400 mg of S-adenosyl-L-methionine per dose, 2 ∼ 3 times daily, orally for 15 ∼ 30 days. - Maintenance treatment: Administer 200 mg per dose orally 2 ∼ 3 times daily. Swallow this drug whole without chewing or crushing.

This medication should not be used by certain patients. First, patients who are allergic to this drug or its ingredients should not take it. Additionally, patients with schizophrenia or bipolar disorder, children, women who are pregnant or may become pregnant, breastfeeding women, and patients with homocystinuria or hyperhomocysteinemia should not take this medication. This medication contains the dye Yellow No. 5, so patients with allergies or hypersensitivity to this dye should use it with caution. When taking this medication, multiple side effects may occur. For example, serious allergic reactions may occur such as swelling of the face, stiffness of the tongue and throat, difficulty breathing, rapid heartbeat, and sharp drops in blood pressure. Gastrointestinal issues may manifest occasionally as discomfort, nausea, vomiting, mild abdominal pain, or gastrointestinal bleeding, and constipation, abdominal bloating, or indigestion may rarely occur. Skin reactions including rash, itching, and urticaria may appear, and sometimes there may be difficulty sleeping, dry mouth, headache, or fatigue. Additionally, caution is needed as there may be an increased risk of suicidal behavior in individuals under 25 years old taking this medication. In older patients over 65 years or those on long-term treatment, caution should be exercised due to a lack of sufficient clinical data. It is advisable not to take this medication if you are pregnant or breastfeeding. There is not enough experience with the use of this medication during pregnancy, nor is it known whether it passes into breast milk. Finally, if this medication is stored in a damaged container or exposed to heat for a prolonged period, it is safer not to use it and to exchange it.

• Facial swelling
• stiffness of the tongue and larynx
• asthmatic breathing difficulties
• tachycardia
• sudden drop in blood pressure
• shock
• gastrointestinal discomfort
• nausea
• vomiting
• mild abdominal pain

This medication should be stored in a sealed container to prevent air exposure and kept at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness and prevents deterioration.

Appearance

Pale yellow, round enteric-coated tablet

Package unit

100 tablets (10 tablets/Foil×10)