Medication info
Exoperin Tablet 50 mg (Eperisone Hydrochloride)

Exoperin Tablet 50 mg (Eperisone Hydrochloride)

Prescription medication경구
Ingredient · strength
Eperisone Hydrochloride›50mg / 1 tablet
Manufacturer / importer
한미약품(주)
Appearance
White circular film-coated tablet
Packaging
30 tablets, 300 tablets/bottle
Approval status
Active

MFDS item code 200003110 · Notified 2000.07.24 · Insurance code 643501890

Summary

Main use
Treatment of musculoskeletal disorders (painful muscle spasm) and neurological disorders (spastic paralysis)
Who takes it
Adults
Adult dose
As Eperisone Hydrochloride, 50 mg orally, three times a day after meals. Adjust dosage as appropriate based on age and symptoms.

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Treatment of musculoskeletal disorders (painful muscle spasm) and neurological disorders (spastic paralysis)

  • Painful muscle spasms
  • shoulder-hand syndrome
  • periarthritis of the shoulder
  • back pain
  • spastic paralysis
  • cerebrovascular accidents
  • spastic spinal paralysis
  • cervical spondylosis
  • postoperative sequelae
  • post-trauma sequelae
  • amyotrophic lateral sclerosis
  • cerebral palsy
View approved original text

This medication is effectively used for painful muscle spasms due to musculoskeletal disorders, such as shoulder-hand syndrome, periarthritis of the shoulder, and back pain. It also helps relieve stiffness due to various neurological conditions such as symptoms of spastic paralysis caused by neurological disorders, cerebrovascular accidents, spastic spinal paralysis, and sequelae of spinal cord injury. This drug contributes to improving patients' movement and daily life by alleviating excessive muscle tension. It helps reduce muscle stiffness and pain across various diseases, improving the quality of life for patients. It is used for the treatment of muscle stiffness and pain occurring in musculoskeletal and neurological disorders.

How to take

Adult dose

As Eperisone Hydrochloride, 50 mg orally, three times a day after meals. Adjust dosage as appropriate based on age and symptoms.

Precautions

This drug should not be used by certain patients. First, persons allergic to this medication should not take it. Furthermore, patients with severe myasthenia gravis, where the muscles are very weak, should not use this drug. This drug contains lactose, so individuals with a genetic disorder that prevents lactose digestion should not take it. When using this medication, patients who have had allergic reactions to this drug or those with liver function problems should use it with caution. Since liver function may deteriorate, individuals with liver dysfunction should take it carefully under the guidance of a physician. Severe allergic reactions, such as shock, may rarely occur while taking this drug, so if symptoms appear, discontinue use immediately and seek appropriate treatment. Since liver enzyme levels may rise abnormally, liver function tests should be performed, and medication should be stopped if abnormal symptoms occur. It may also affect kidney function, so if proteinuria or abnormalities are found in blood tests, the medication should be discontinued. Blood abnormalities, such as anemia, can occur rarely, so symptoms should be observed closely. Hypersensitivity reactions, such as skin rash or itching, may occur. Neurological symptoms such as insomnia, drowsiness, headache, and tingling in limbs have also been reported, requiring caution. Gastrointestinal symptoms including nausea, vomiting, decreased appetite, abdominal pain, diarrhea, etc., may also occur. Urinary symptoms, such as difficulty urinating or a feeling of incomplete bladder emptying, may rarely occur. General symptoms such as weakness, dizziness, and decreased muscle tone may also be experienced. Other symptoms, such as facial flushing or excessive sweating, and swelling may also arise. In particular, serious skin adverse reactions, such as toxic epidermal necrolysis or Stevens-Johnson syndrome, may occur, so if symptoms such as skin rash, blisters, eye redness, and oral mucosa lesions appear, discontinue use immediately. Drowsiness or decreased concentration may occur while taking this drug, so driving or operating dangerous machinery should be avoided. Caution is warranted when using this drug with similar medications or muscle relaxants, as vision impairment may occur. Women who are pregnant or may become pregnant should only take this drug after consulting a physician, as its safety has not been established. Women who are breastfeeding should avoid taking this drug, and if necessary, should discontinue breastfeeding during its use. Safety has not been sufficiently established for children, so care is needed for their use. Elderly individuals may have decreased bodily functions; therefore, careful observation and dose adjustment may be required.

Side effects and when to seek care immediately

Serious side effects

Shock, anaphylaxis, angioedema, toxic epidermal necrolysis and mucocutaneous syndrome, elevated ALT, elevated AST, elevated ALP, proteinuria, elevated BUN, anemia

Mild side effects

  • Rash
  • itching
  • insomnia
  • drowsiness
  • headache
  • limb paralysis
  • body stiffness
  • limb tremors
  • nausea
  • vomiting
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  • loss of appetite
  • dyspepsia
  • dry mouth
  • constipation
  • diarrhea
  • abdominal pain
  • abdominal bloating
  • oral mucosa lesions
  • urinary retention
  • urinary incontinence
  • feeling of incomplete bladder emptying
  • weakness
  • staggering
  • general fatigue
  • dizziness
  • decreased muscle tone
  • facial flushing
  • sweating
  • drowsiness
  • decreased attention
  • decreased concentration
  • decreased reflex motor ability

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly sealed container to prevent air or moisture from entering, and it is best stored at room temperature between 1 and 30 degrees Celsius. By storing it this way, the effectiveness of the drug can be maintained for a long time.

Appearance and packaging

Appearance

White circular film-coated tablet

Package unit

30 tablets, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.