Levorem Tablets (Levosulpiride)

Adult dose

Adults: Administer 25 mg of levosulpiride orally 3 times daily before meals.

This medication should not be used by women who are pregnant or may become pregnant, and those who are breastfeeding. This medication should not be administered to patients with gastrointestinal bleeding, mechanical obstruction, perforation, etc., as it may stimulate gastrointestinal motility and worsen the condition. Patients with certain tumors such as pheochromocytoma should avoid this medication as it may cause hypertension. Patients who are allergic to this medication or have difficulty tolerating it should also avoid administration. Patients with epilepsy, manic states, or the manic phase of bipolar disorder may experience worsened symptoms and should not use this medication. Patients with breast-related conditions should use this medication with caution, as it may affect hormone secretion, potentially causing breast problems. This medication contains lactose; patients with genetic issues such as lactose intolerance, lactose deficiency, or glucose-galactose malabsorption should not take it. Patients with hypertension, children, and the elderly should use this medication with caution, and particularly in children, the dosage must be adjusted. While taking this medication, hormonal abnormalities such as amenorrhea, galactorrhea, and gynecomastia may occur, and if any abnormal symptoms appear, the use of the medication should be immediately discontinued. Rarely, neurological symptoms such as tremors, tongue twisting, and agitation may present, requiring discontinuation of treatment. Prolonged use may lead to involuntary movements around the mouth, which can persist even after discontinuation of the medication. Occasionally, gastrointestinal symptoms such as dry mouth, heartburn, nausea, vomiting, diarrhea, or constipation may occur. Cardiac-related abnormal symptoms such as hypertension or arrhythmia may also appear rarely, requiring careful attention. There is a risk of developing a serious adverse effect known as neuroleptic malignant syndrome, which can occur with high fever, muscle rigidity, and altered consciousness, requiring immediate treatment. If a rash or swelling occurs, the use of this medication should be stopped, and occasionally, flushing, fatigue, insomnia, drowsiness, dizziness, unsteadiness, erectile dysfunction, or changes in libido may occur. Long-term use may lead to menstrual irregularities, gynecomastia, galactorrhea, and changes in libido due to hormonal imbalances, although most of these are recoverable. This medication can affect the nervous and endocrine systems, so it should be taken cautiously under medical supervision. It is advisable to avoid activities requiring concentration, such as driving or operating machinery, while taking this medication. This medication is also used as an atypical antipsychotic in some countries and may rarely cause cardiac rhythm abnormalities, so special caution should be exercised for patients with heart conditions. Interactions may occur when taking it with other medications, especially anticholinergics, opioid analgesics, digitalis preparations, other benzamide medications, psychopharmacological medications, drugs that prolong the QT interval, and drugs that cause electrolyte disturbances, so these should not be combined or monitored closely. Pregnant or breastfeeding women should not use this medication as it may harm the fetus or newborn. Elderly individuals with weakened kidney function may retain the medication in their bodies for longer, so dosage adjustment and monitoring for side effects are essential. This medication may suppress vomiting symptoms and should be used cautiously depending on the cause of vomiting. Animal studies have reported risks of reproductive dysfunction and tumor occurrence; thus, caution is necessary for long-term use.

• Amenorrhea
• excessive milk secretion
• gynecomastia
• tremor
• tongue twisting
• anxiety
• involuntary movements
• thirst
• heartburn
• nausea

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. The storage temperature should be maintained between 1 degree and 30 degrees Celsius at room temperature. This helps to preserve the effectiveness of the medication for a longer time.

Appearance

White round tablet

Package unit

Domestic - 30 tablets/bottle, Domestic - 300 tablets/bottle, Domestic - 500 tablets/bottle, Export - 100 tablets/PTP [(10 tablets/PTP x 10)]