Jedin Tablet 150 mg (Ranitidine Hydrochloride)

Adult dose

For adults, the dose is 150 mg taken orally twice a day, in the morning and at bedtime. For gastric and duodenal ulcers, 150 mg can be taken orally twice a day or 300 mg once a day at bedtime. For duodenal ulcer patients, 300 mg can be administered orally twice a day. For ulcer prevention caused by NSAID use, the dosing regimen is the same.

Child dose

Children aged 8 to 18 can be given 150 mg (2 mg per kg of body weight) once, up to twice a day.

This medication should not be used in patients with a known allergy to any of its components or those with a history of acute porphyria. It should be used cautiously in patients with impaired kidney function, as the drug may remain in the body longer; thus, dosage reduction or extended dosing intervals is necessary. Caution is also advised for patients with compromised liver function or a history of drug allergies, elderly patients, and those taking NSAIDs. Particularly, patients with gastric ulcers or those over middle age who have newly developed or experienced changes in dyspeptic symptoms should confirm the possibility of gastric cancer before using this medication. This drug should be administered in conjunction with eradication therapy for patients with gastric or duodenal ulcers caused by Helicobacter pylori. Severe allergic reactions, such as anaphylactic shock, may occur rarely; any unusual symptoms should prompt immediate cessation of the medication and consultation with healthcare professionals. Blood tests may reveal abnormalities such as leukopenia and thrombocytopenia; notify a hospital immediately if you experience weakness, bleeding, or fever. The liver function may deteriorate temporarily; if symptoms such as jaundice, fatigue, or loss of appetite occur, stop the medication and consult a physician. Arrhythmias, vasculitis, gastrointestinal symptoms (constipation, nausea, abdominal pain, etc.), and neuropsychiatric symptoms (dizziness, drowsiness, confusion, etc.) may also occur rarely, necessitating caution. This drug has been reported to cause side effects such as gynecomastia, erectile dysfunction, myalgia, and skin rashes, so seek immediate medical advice if you have any unusual symptoms. Elderly patients or those with reduced kidney function may have higher blood drug concentrations, requiring dosage adjustments. While taking this medication, if dizziness or drowsiness occurs, avoid driving or operating hazardous machinery. Interactions with other drugs may occur, so always inform your healthcare provider of any medications you are taking, especially anticoagulants like warfarin, and regularly monitor blood coagulation status when using them concurrently. Women who are pregnant or may become pregnant and breastfeeding mothers should only use this medication after careful consideration when absolutely necessary. The safety for use in children has not been fully established, so special caution is warranted.

Serious side effects

Urticaria, angioedema, shock (anaphylactic shock), bronchospasm, vascular edema, hematological abnormalities (granulocytopenia, leukopenia, thrombocytopenia, bone marrow suppression, aplastic anemia, agranulocytosis, pancytopenia, acquired immune hemolytic anemia), liver abnormalities (jaundice, liver dysfunction, hepatitis), bradycardia, heart block, tachycardia, vasculitis, acute pancreatitis, seizures, severe headache, confusion, altered consciousness.

Mild side effects

• Rash
• fever
• hypotension
• chest pain
• constipation
• nausea
• vomiting
• abdominal bloating
• abdominal pain
• loss of appetite

Store this medication in a tightly sealed container to prevent air exposure, at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the drug's effectiveness and prevents degradation.

Appearance

White round film-coated tablet

Package unit

100 tablets (10 tablets/PTP x 10)