Medication info
Nolvadex D Tablets (Tamoxifen Citrate)

Nolvadex D Tablets (Tamoxifen Citrate)

Prescription medicationTabletOral
Ingredient · strength
Tamoxifen Citrate›30.4mg / 1 tablet
Manufacturer / importer
AstraZeneca Korea
Appearance
White to off-white octagonal tablets
Packaging
30 tablets (10 tablets/PTP × 3)
Approval status
Active

MFDS item code 199907054 · Notified 1999.12.22 · Insurance code 650700100

Summary

Main use
Treatment of breast cancer
Who takes it
Adults
Adult dose
Administer 20~40 mg of tamoxifen orally to adults per day in 2 divided doses (morning and evening). Adjust the dose as appropriate according to symptoms.

Ingredients

Importer
AstraZeneca Korea

Efficacy & effects

Treatment of breast cancer

  • Breast cancer
View approved original text

This medication is used for the treatment of breast cancer.

How to take

Adult dose

Administer 20~40 mg of tamoxifen orally to adults per day in 2 divided doses (morning and evening). Adjust the dose as appropriate according to symptoms.

Precautions

This medication should not be used in women who are pregnant or may become pregnant. Patients who are allergic to this drug or its components should also refrain from taking it. Caution is required as the risk of side effects may increase when taken in conjunction with certain other medications. This medication contains lactose, so it should not be used in patients with lactose intolerance or related genetic disorders. Patients with leukopenia or thrombocytopenia should use this medication with caution. During treatment, symptoms such as nausea, vaginal bleeding, skin rash, flushing, fatigue, and depression may occur, and in severe cases, it may be necessary to reduce or discontinue the dosage. Rarely, vision disturbances, liver dysfunction, thrombosis, endometrial changes, and hair loss may occur, so any abnormal symptoms should be consulted with a doctor immediately. While taking this medication, it is essential to avoid pregnancy and fertile women should use effective non-hormonal contraception. Regular check-ups are needed if there are any endometrial abnormalities or abnormal vaginal bleeding. As the risk of thrombosis may be increased, thorough inquiry into the patient and family history is recommended, and preventive anticoagulation therapy may be advised if necessary. Extra caution is particularly important for thrombosis prevention in cases of surgery or prolonged immobility. This medication may interact with drugs that affect liver metabolism, so if you are taking other medications, be sure to inform your doctor or pharmacist. Special caution is needed when taken with specific antidepressants or antituberculosis drugs. It is safe to avoid using this medication in pregnant or breastfeeding women, and if it must be used, breastfeeding should be discontinued. Safety in pediatric patients has not been established, thus it is not recommended.

Side effects

  • Nausea
  • fluid retention
  • vaginal bleeding
  • vaginal discharge
  • skin rash
  • flushing
  • fatigue
  • depression
  • anemia
  • cataract
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  • retinopathy
  • hypersensitivity reaction
  • increased triglycerides
  • leg cramps
  • myalgia
  • uterine fibroids
  • ischemic cerebrovascular disease
  • headache
  • dizziness
  • sensory disorder
  • vulvar itching
  • endometrial changes
  • hair loss
  • vomiting
  • diarrhea
  • constipation
  • changes in liver enzyme levels
  • fatty liver
  • thromboembolic reaction
  • thrombocytopenia
  • leukopenia
  • vision impairment
  • pancreatitis
  • hypercalcemia
  • endometrial cancer
  • interstitial pneumonia
  • cirrhosis
  • hepatitis
  • cholestasis
  • liver failure
  • hepatocellular damage
  • liver necrosis
  • angioedema
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • skin vasculitis
  • bullous pemphigoid
  • erythema multiforme
  • endometriosis
  • cystic ovarian enlargement
  • vaginal polyps
  • cutaneous erythematous lupus
  • hepatic porphyria
  • radiation recall
  • insomnia
  • depressive mood
  • loss of appetite
  • abdominal pain
  • deep vein thrombosis
  • cerebral thrombosis
  • lower extremity venous thrombophlebitis
  • phlebitis
  • amenorrhea
  • menstrual irregularities
  • uterine myomas
  • ovarian cysts
  • ovarian cysts
  • sweating
  • retinal atrophy
  • optic nerve atrophy
  • vision decrease
  • blurred vision
  • weight gain
  • edema
  • bone pain
  • malaise
  • increased urination

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. Therefore, it is essential to keep the container well closed when using the medication.

Appearance and packaging

Appearance

White to off-white octagonal tablets

Package unit

30 tablets (10 tablets/PTP × 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.