Hanmi Famotidine 20mg Tablets (Famotidine)

Adult dose

1. Gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding (due to peptic ulcers, acute stress ulcers, hemorrhagic gastritis), gastroesophageal reflux disease, Zollinger-Ellison syndrome: 20mg orally twice daily (after breakfast and after dinner or at bedtime) or 40mg orally once daily (at bedtime). For upper gastrointestinal bleeding, treatment usually begins with parenteral administration and once oral administration is feasible, it is switched to oral administration.

This medication should not be used in patients who have had an allergic reaction to this drug's ingredients or other H2 receptor antagonists. This drug contains lactose, thus patients with a genetic disorder that impairs the digestion of lactose should not take it. Patients with a history of drug allergies or those with impaired renal function need to be cautious when using this drug. Patients with heart diseases or impaired liver function should also monitor their condition closely when taking this medication. Elderly individuals may experience deteriorating renal function, so the dosage should be reduced or the interval extended. If allergic to any of the dyes contained in this medication, it should be carefully administered. Though rare, serious allergic reactions, blood disorders, skin diseases, liver dysfunction, muscle damage, cardiac rhythm disturbances, consciousness difficulties, nephritis, pneumonia, or other side effects may occur; if any symptoms arise, the medication should be stopped immediately and medical attention sought. During treatment, symptoms and blood, liver, and kidney functions should be regularly checked for abnormalities. Dialysis patients taking this medication with certain phosphate binder agents should be cautious as drug effectiveness may be reduced. This medication may affect drug concentration and effectiveness when taken with some antifungals or anticancer agents, so consultation with medical personnel regarding concurrently taken medications is essential. Women who are pregnant or may become pregnant should only take this medication if the benefits of treatment are deemed greater than the risks, and its safety has not been fully established. Breastfeeding women are advised to discontinue nursing as this medication may be excreted in breast milk. Safety in children has not been fully established, so it should be used with caution in pediatric patients. This medication may mask symptoms of gastric cancer, so it should only be used after confirming that it is not gastric cancer.

Serious side effects

Shock, hypersensitivity (anaphylaxis, respiratory distress, generalized flushing, angioedema <facial swelling, laryngeal edema, etc.>, urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia (early symptoms: generalized malaise, weakness, subcutaneous and mucosal bleeding, fever), Stevens-Johnson syndrome (mucocutaneous syndrome), Lyell syndrome (toxic epidermal necrolysis), liver dysfunction, jaundice, rhabdomyolysis (hyperkalemia, myoglobinuria, serum abnormalities)

Mild side effects

• Hypersensitivity
• rash
• urticarial (erythema)
• facial swelling
• leukopenia
• eosinophilia
• constipation
• diarrhea
• dry mouth
• nausea

This medication should be stored in a tightly closed container to prevent air and moisture exposure, and should be kept in a cool place away from direct sunlight.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle