Enanthate of Testosterone Injection

Adult administration

The treatment initiation should be a slow intramuscular injection of 250 mg of testosterone enanthate every 2 to 3 weeks. The dosing interval should be personalized based on the clinical response and severity of testosterone deficiency. Serum testosterone levels should be measured before treatment and during the injection period; if they are higher than normal, the injection interval may be extended, and if lower than normal, it may be shortened.

This medication should not be used by healthy individuals to enhance strength or physical fitness. It should not be used by patients with certain medical conditions. For example, patients with androgen-dependent tumors, prostate cancer, pregnant women or women who may become pregnant, patients with liver tumors, male breast cancer patients, those with hypercalcemia, patients with kidney disease, and those who are allergic to this medication or its components. Additionally, patients with hypertension, migraines, epilepsy, diabetes, tendencies for edema, benign prostatic hyperplasia, history of heart or kidney disease, patients with bone metastases from cancer, and elderly individuals should exercise extra caution when using this medication. This medication can cause various side effects, including masculinization symptoms in women, suppression of sperm production, precocious puberty in boys, gynecomastia in men, erectile problems, and accelerated bone maturation. There can also be liver function abnormalities, jaundice, liver enlargement, mental health issues, headaches, skin changes, acne, itching, fluid retention, edema, and pain at the injection site. In serious cases, circulatory problems such as thrombosis and pulmonary embolism have been reported, so if symptoms are suspected, a doctor should be consulted immediately. Serious liver issues, such as liver tumors or intra-abdominal bleeding, may occur rarely, and immediate assessment should be sought if there are signs of upper abdominal pain or other unusual symptoms. This medication can affect blood coagulation; therefore, patients taking anticoagulants may need dosage adjustments. Furthermore, when taken with certain drugs that induce liver enzymes, the efficacy of this medication may be diminished. Pregnant women should not use this medication as it poses the risk of causing masculinization of the fetus. The safety and effectiveness of this medication have not been established in children or adolescents, and its use is not recommended. Elderly individuals have reduced bodily function and may have increased risks for certain tumors, so they should be particularly cautious when using this medication. It should be injected very slowly into the muscle, being careful with the injection site and method to avoid nerve or tissue damage. If there is pain or unusual symptoms at the injection site, the injection site should be changed immediately. Lastly, long-term high-dose use of this medication may increase the risk of liver tumors, so regular health check-ups are necessary.

Serious side effects

• Hives
• edema
• jaundice
• headaches.

Mild side effects

Masculinization in women (irreversible voice changes, seborrhea, hirsutism), suppression of sperm formation, precocious puberty in boys, gynecomastia in men, frequent or persistent erections, accelerated bone maturation, hypersensitivity reactions, abnormal liver function test results, liver enlargement, euphoria, depression, anxiety, headaches, sensory disturbances, male-pattern baldness, skin color changes, acne, rashes, itching, hypercalcemia, fluid retention, pain and sclerosis at the injection site, edema, pain.

This medication should be stored at room temperature between 1°C and 25°C, in a sealed container to avoid contact with air. It is also important to store it in a dark place to protect it from light, which may degrade its efficacy.

Appearance

A transparent pale yellow oily liquid contained in a brown ampoule.

Package unit

1ml/ampoule x 10 ampoules/box