Lobafen Tablets (Loxoprofen Sodium)

Adult dose

1. For indications 1 and 2: Adults should take 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For single-use therapy, take 60-120 mg orally. 2. For indication 3: Adults should take 60 mg of loxoprofen sodium (anhydrous) orally. Generally, it can be administered twice a day, with a maximum daily dose of 180 mg. It is advisable to avoid taking it on an empty stomach.

People who regularly consume more than three alcoholic beverages a day must consult a physician or pharmacist before taking this medication due to the risk of gastric bleeding. This medication can also affect the cardiovascular system, increasing the risk of serious cardiovascular diseases such as myocardial infarction or stroke. Particularly, patients with cardiovascular diseases or risk factors need to exercise caution and monitor symptoms closely with a physician. This drug may cause serious gastrointestinal adverse reactions such as gastric and intestinal bleeding, ulcers, and perforation. Elderly individuals or those with a history of gastrointestinal diseases are at a higher risk, so gastrointestinal symptoms should be monitored carefully during use. Patients with a history of peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, heart failure, or allergies to this medication or its components should not take this drug. Additionally, patients with allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs, pregnant women in late pregnancy, nursing mothers, and patients with inflammatory bowel disease should also avoid use. Patients with a history of peptic ulcers or problems with liver and kidney function, elderly individuals, patients with hypertension, patients with bleeding disorders or those on anticoagulants should exercise caution when taking this drug. If hypersensitivity reactions such as skin rash, itching, difficulty breathing, or low blood pressure occur, the medication should be stopped immediately and medical attention sought. Gastrointestinal symptoms may include abdominal pain, nausea, vomiting, diarrhea, and bloody stool, with severe cases requiring immediate treatment. This medication may cause neurological side effects such as drowsiness, dizziness, and headache, and abnormal liver and kidney function may also occur, necessitating regular tests and monitoring. Rarely, heart failure, edema, interstitial pneumonia, and severe skin reactions (such as Stevens-Johnson syndrome) may occur, and symptoms should be discussed with a physician immediately. Long-term use of this medication can cause kidney damage or anemia; thus, regular blood tests and kidney function tests are needed during prolonged usage. Drug interactions with other non-steroidal anti-inflammatory drugs or specific medications might increase the risk of adverse effects, so it is essential to consult healthcare professionals. This medication should not be used during pregnancy, especially in the late stages, as it may pose risks to the fetus, and it should also not be used while breastfeeding. The safety in children has not been established; therefore, caution should be exercised when used in this population. Elderly patients may be more sensitive to the side effects of this drug and should be monitored closely during use. Lastly, this medication should be stored out of reach of children and not transferred to other containers for safety.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweats, paleness, severe allergic reactions; severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin adverse reactions; asthma attacks, respiratory abnormalities accompanied by cough and fever, breathing difficulties; yellowing of the skin or eyes (jaundice), severe lethargy, liver abnormalities (jaundice); sudden and severe headaches, lightning-like headaches, seizures.

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the stomach area
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, and it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a longer duration.

Appearance

Light pink round tablets.

Package unit

30 tablets/bottle, 200 tablets/bottle