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Prescription medication

Tobrex 0.3% Eye Drops (Tobramycin)

Treatment of ocular infections such as blepharitis, conjunctivitis, etc.

Novartis Korea Co., Ltd.

Key information summary

Efficacy & effects
Treatment of ocular infections such as blepharitis, conjunctivitis, etc.
Adult dosage
For mild to moderate infections, instill 1-2 drops in the affected area every 4 hours. For severe infections, instill 2 drops every hour until symptoms improve, then gradually taper off. Adjust according to age and symptoms.
Ingredients
Tobramycin
Rx / OTC
Prescription medication
Appearance
An eye drop solution that is colorless, transparent to light yellow-brown, contained in an opaque white plastic bottle.

Efficacy & effects

This medication is effective against various bacteria including Staphylococcus, Streptococcus, Pseudomonas, and Escherichia coli, and is used for the treatment of eye-related inflammations such as blepharitis, dacryocystitis, stye, conjunctivitis, keratitis, and corneal ulcers. It is particularly useful for treating infections around and inside the eye and can be effective against penicillin-resistant bacteria, potentially aiding in the issue of antibiotic resistance. This medication works broadly against various types of bacteria to help improve infections quickly. Patients may expect significant relief of symptoms and effective treatment of infections when used exactly as directed. This medication is used to safely and effectively improve eye disorders.

Dosage

For mild to moderate infections, instill 1-2 drops in the affected area every 4 hours. For severe infections, instill 2 drops every hour until symptoms improve, then gradually taper off. Adjust according to age and symptoms.

Precautions

This medication is an aminoglycoside antibiotic used to treat bacterial infections in the eye. It should not be used by individuals with a hypersensitivity to this medication or those who are allergic to aminoglycoside antibiotics or bacitracin. During use, symptoms such as discomfort or congestion in the eyes, headache, skin rash, and itching may occur; hence caution is advised. Rarely, severe allergic reactions, inflammation of the eyes, or skin conditions may arise, so if any abnormal symptoms appear, use should be stopped immediately, and a healthcare professional should be consulted. To prevent resistance, it is recommended to use this medication only for the necessary duration and to avoid long-term or repeated use. Contact lens wearers must remove their lenses while using this medication and can reinsert them after a certain period, and it is safest to avoid wearing lenses during treatment. Using this medication may temporarily blur vision; hence, driving or operating machinery should not be done until vision returns to normal. If hypersensitivity occurs, use should be stopped immediately and healthcare personnel should be informed; caution is advised as there may be allergies to other aminoglycoside drugs as well. Patients with suspected or known neuromuscular disorders should use this medication cautiously as it may worsen muscle weakness. Combine with anticoagulants with caution as the risk of bleeding may increase, necessitating regular checks of blood coagulation status and possible adjustments to medication dosage. During pregnancy, it should only be used when absolutely necessary, and while breastfeeding, a decision should be made based on the benefits versus risks, including whether to suspend breastfeeding or to discontinue medication use. In case of overdose, eye irritation, inflammation, and swelling may occur, and blood levels of the drug should be checked, with possible treatments like dialysis if needed. This medication is to be used only for ophthalmic purposes and should not be used after 4 weeks from the first opening; dispose of after this period. When using, care should be taken to avoid contact of the tip of the bottle with the eye or surrounding areas to prevent contamination, and after instillation, it is advisable to close the eyes and occlude the nasolacrimal duct to minimize systemic absorption. When using other ophthalmic medications, they should be administered with a minimum interval of 5 minutes, and if an ointment is used, it should be applied last.

Side effects

Urticaria, anaphylactic reactions, Stevens-Johnson syndrome, erythema multiforme

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