Midriacil 1% Eye Drops (Tropicamide)

Adult eye dose

Paralytic refraction: Instill 1-2 drops at intervals of 5 minutes; if not seeing well within 20-30 minutes, additional drops may be instilled to maintain mydriatic effect. Fundoscopy: Instill 1 drop 15-20 minutes before the examination. Adjust dosage appropriately according to symptoms.

This medication should not be used in patients at risk for glaucoma or angle-closure glaucoma. Those with allergies to the components contained in this medication should also avoid administration. Use cautiously in children or patients sensitive to this medication, as there is a risk of systemic toxicity. During use, side effects such as increased intraocular pressure, mental changes, behavioral disorders, heart and respiratory issues, skin rashes, and abdominal distention may occur. Temporary side effects may include eye pain, dry mouth, blurred vision, glare, rapid heartbeat, and allergic reactions. Long-term use may cause irritation, congestion, swelling, or conjunctivitis around the eyes. Systemically, there may be dry skin, arrhythmias, reduced sweating, urinary issues, constipation, dizziness, and vomiting, with severe central nervous system disturbances particularly in children. This medication can increase intraocular pressure and may trigger angle-closure glaucoma, thus caution is necessary in patients at risk for glaucoma. Psychotic symptoms and behavioral disorders have been reported in children, so extra care is required. This medication contains components that can irritate the eyes and discolor soft contact lenses, so lenses should be removed before use and replaced at least 15 minutes after administration. Intraocular pressure and the condition of the eye's anterior segment should be checked before administration. To reduce systemic absorption, it's advised to press the tear duct area for more than 1 minute after administration. This medication may cause drowsiness or blurred vision and increased sensitivity to light, so driving or operating hazardous machinery should be avoided. The safety in patients with impaired liver or kidney function is unclear, hence caution is advised. The effects may be enhanced when used in conjunction with other anticholinergic medications, so consultation with a doctor is required. Pregnant or nursing women should not use this medication as its safety has not been established, and the necessity of treatment should be carefully considered. For children, use the product with the lowest concentration possible, and avoid using concentrations higher than 0.5% in infants, as excessive use may lead to systemic toxicity. In cases of overdose, symptoms such as dry skin, flushing, blurred vision, rapid heartbeat, convulsions, and hallucinations may occur, and it is important to rinse the eyes with lukewarm water immediately and induce vomiting and perform gastric lavage if necessary. It should only be used as eye drops, taking care that the tip of the container does not come into direct contact with the eye to prevent contamination. It is advisable to block the tear duct or gently close the eyelid after administration to reduce systemic absorption, and when using with other eye drops, allow a minimum interval of 5 minutes, and it is safest to use ointments last. This medication should be stored out of the reach of children, away from direct sunlight, in a cool place, and it is important not to transfer it to another container to maintain quality.

Serious side effects

Rash, swelling, allergic reactions, blurred vision, difficulty breathing (including cardiovascular collapse), central nervous system disorders due to systemic anticholinergic toxicity, loss of neuromuscular coordination, convulsions, hallucinations, cardiovascular collapse, potential decreased urine output, edema including increased blood pressure, severe skin reactions, central nervous system disorders, severe allergic reactions.

Mild side effects

Increased intraocular pressure, mental reactions, behavioral disorders, cardiovascular collapse, rash, abdominal distention, eye pain, dry mouth, blurred vision, glare, tachycardia, parasympathetic nervous system stimulation, allergic reactions, local irritation, congestion, swelling, conjunctivitis, flushing, dryness of mucous membranes, skin dryness, bradycardia, palpitations, arrhythmias, decreased sweating, frequent urination, urinary disorders, reduced secretion in the nose, bronchi, and tears, constipation, reduced gastrointestinal motility, dizziness, vomiting.

This medication should be stored in a tightly sealed container to avoid contact with air or moisture. It is also recommended to store it at room temperature, avoiding extremes of heat or cold.

Appearance

A colorless, clear solution in a colorless translucent plastic container, used as an eye drop.

Package unit

15 milliliters/bottle - 15 milliliters/bottle