Hanapephrine Hydrochloride Injection 1%

Adult administration

Generally administered via subcutaneous injection, intramuscular injection, slowly via intravenous injection, or continuously through infusion. 1. Moderate hypotension 1) Subcutaneously or intramuscularly: The usual dosage is 2-5mg, administered within a range of 1-10mg. The initial dose should not exceed 5mg. 2) Intravenous injection: The usual dosage is 0.2mg, administered within a range of 0.1-0.5mg. The initial dose should not exceed 0.5mg.

Child administration

For hypotension during spinal anesthesia, it is recommended to administer 0.5-1mg/25 pounds (11.34 kg) subcutaneously or intramuscularly.

This medication stimulates the sympathetic nervous system to elevate blood pressure. It may cause serious side effects, such as severe hypertension or cerebral vascular rupture, if used in conjunction with drugs that induce uterine contractions. Individuals allergic to sulfites may experience severe allergic reactions or asthma symptoms due to the components contained in this medication, so caution is advised. Patients with hypertension or rapid heart rate, as well as those with known allergies to this drug, should not use it. Elderly patients, those with hyperthyroidism, those with bradycardia or conduction problems, and individuals with heart disease or severe atherosclerosis should use this drug cautiously. Users should monitor for symptoms such as headache, bradycardia, anxiety or agitation, and occasionally arrhythmias while using the drug. When used with other antihypertensives or certain antidepressants, there is an increased risk of cardiac side effects, so caution is necessary. It is advisable not to use this medication during pregnancy unless absolutely necessary, and adequate studies on its effects on the fetus have not been conducted. Discretion is required when used by nursing mothers and children, following medical advice. In case of overdose, symptoms may include cardiac rhythm disturbances, headache, and peripheral pain, and immediate treatment is necessary if blood pressure rises excessively. Before use, check externally to confirm that the drug has not been discolored or contaminated and store it in a sealed container protected from light, maintaining a temperature between 15 to 30 degrees Celsius.

Serious side effects

• Severe hypertension
• ventricular tachycardia
• anaphylaxis symptoms
• severe asthma symptoms

Mild side effects

• Headache
• reflex bradycardia
• agitation
• anxiety
• rarely arrhythmias
• ventricular extrasystole
• transient ventricular tachycardia
• heaviness
• pain in extremities

This medication should be stored in a sealed container that blocks out light, and it is important to maintain a storage temperature between 15 and 30 degrees Celsius. This way of storage helps in retaining the drug's effectiveness and preventing degradation.

Appearance

A colorless and transparent liquid in a brown vial injection

Package unit

1mL x 10 vials