Medication info

Dosmin Tablet (Pyridostigmine Bromide)

Prescription medicationApproval withdrawn
Ingredient · strength
Pyridostigmine Bromide›Strength being verified
Manufacturer / importer
Hana Pharmaceutical Co., Ltd.
Appearance
White round tablet
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Approval withdrawn

MFDS item code 199702352 · Notified 1997.02.19

This product's status changed to Approval withdrawn on 2023.04.04. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of myasthenia gravis
Who uses it
Adults
Adult dosage
Adults: Administer pyridostigmine bromide orally at a daily dose of 60-180㎎ in 3 divided doses. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Hana Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of myasthenia gravis

  • Myasthenia gravis
View approved original text

Myasthenia gravis is a disorder characterized by weakness and easy fatigue in the muscles due to problems with the transmission of signals between nerves and muscles. This medication helps improve muscle function and alleviate symptoms in patients with myasthenia gravis.

Dosage and Administration

Adult dosage

Adults: Administer pyridostigmine bromide orally at a daily dose of 60-180㎎ in 3 divided doses. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medicine should not be used in certain patients. For example, patients with an allergy to this drug or similar drugs, those with blockages or spasms in the digestive tract or urinary tract, patients with severe asthma or bronchitis, patients with eye inflammation, those with hyperthyroidism, patients with muscle tone disorders, Parkinson's disease patients, patients with heart or blood circulation issues, patients using certain muscle relaxants, and patients with vagus nerve tension syndrome should not use this drug. Additionally, patients with poor kidney function, history of peptic ulcers, gastrointestinal surgery, diabetes, liver dysfunction, weak heart function, those who have recently experienced a myocardial infarction, patients with arrhythmias or bradycardia, hypotension, coronary artery obstruction, and epilepsy should use this drug with caution. Routine liver function tests are important for those with liver dysfunction. Excessive intake of this drug may cause breathing problems, muscle spasms, abdominal pain, diarrhea, excessive sweating, and constriction of the pupils. If these symptoms occur, stop taking the medication immediately and seek medical treatment. This drug may also cause various side effects such as abdominal pain, nausea, vomiting, increased salivation, tearing, sweating, and increased bronchial secretion, so consult a doctor if symptoms are severe. Especially in patients with myasthenia gravis, symptoms may worsen rapidly, so the dosage should be adjusted according to a specialist's instructions. This drug is primarily excreted through the kidneys, so patients with reduced kidney function should start with a lower dose and adjust based on their condition. Be cautious of interactions when using this drug in conjunction with other medications. Using certain muscle relaxants or anticholinergics together may exacerbate side effects, so co-administration should be avoided or done with extreme caution. Women who are pregnant or breastfeeding should only use this medication when absolutely necessary, as safety has not been fully established. If breastfeeding, it is advisable to discontinue breastfeeding when taking this medication. Elderly patients may have reduced kidney function, which can increase drug concentration, so they should start with a lower dose and be closely monitored.

Side effects

  • respiratory muscle paralysis
  • apoplexy
  • abdominal pain
  • diarrhea
  • sweating
  • flexibility
  • miosis
  • nausea
  • vomiting
  • abdominal distension
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  • excessive salivation
  • tearing
  • bronchial hypersecretion
  • increased peristalsis
  • muscle cramps
  • fibrocystic contractions
  • muscle weakness
  • headache
  • palpitations
  • tinnitus
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a cool, dry place, and it is important to keep it in a tightly sealed container to prevent air exposure.

Appearance and packaging

Appearance

White round tablet

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.