Korea Nelson Misoprostol Tablets (Misoprostol 100 Concentrate)

Adult dose

1. Treatment of gastric and duodenal ulcers and gastroduodenitis and gastric and duodenal ulcers caused by nonsteroidal anti-inflammatory drugs: Take 1 tablet (200㎍ of misoprostol per dose) orally 4 times daily for 4∼8 weeks with meals and at bedtime. 2. Prevention of gastroduodenitis and gastric and duodenal ulcers caused by nonsteroidal anti-inflammatory drugs: Take 2∼4 tablets daily (400∼800㎍ of misoprostol) orally in divided doses with meals and at bedtime. Administer this medicine during treatment with nonsteroidal anti-inflammatory drugs as directed by a physician. To minimize diarrhea, which may occur as an adverse effect, take this medicine with food and avoid concomitant use (taking together) with magnesium-containing antacids. Adjust the dose as appropriate according to age and symptoms.

This medication should not be administered to pregnant women as it may cause miscarriage. Women who may become pregnant must undergo a pregnancy test before taking this medication and must use effective contraception. This medication must not be given to anyone who may become pregnant, and the risks associated with pregnancy while taking it must be thoroughly explained. It should not be used in case of allergy to Misoprostol or any of its other components. Patients at risk of severe blood pressure drop, such as those with cerebrovascular disease or coronary artery disease, should use this medication cautiously. Patients with liver function problems should also take caution when using this medication. Serious allergic reactions, such as shock or difficulty breathing, may occur while taking this medication, so if any symptoms arise, immediately discontinue use and consult healthcare professionals. Gastrointestinal side effects may include diarrhea, abdominal pain, and nausea, and in rare cases, severe diarrhea may lead to dehydration, so caution is needed. This medication can burden the stomach, hence it is advisable not to take it with antacids containing magnesium, and it is recommended to take during meals or at bedtime. Patients with diabetes, gout, or kidney function abnormalities should regularly monitor their condition while taking this medication. Blood-related abnormal symptoms, gynecological bleeding, skin rashes, headaches, dizziness, and other side effects may occur, so if symptoms arise, discuss with healthcare professionals. Exposure to this medication during pregnancy increases the risk of congenital malformations or severe issues for the fetus, thus it should NEVER be taken during pregnancy. Lactating women should also avoid taking this medication as it may affect the baby, making it unsafe for use. Safety has not been established in children, so use is not recommended. Elderly patients should be cautious as dosage adjustment or discontinuation may be needed if gastrointestinal side effects occur. In case of overdose, symptoms such as severe diarrhea, uterine contractions, hypotension, and difficulty breathing may appear, and immediate medical attention is necessary. This medication should be stored out of reach of children and should not be transferred to another container for safety.

• Shock
• anaphylactic reactions
• diarrhea
• abdominal pain
• nausea
• abdominal distension
• loss of appetite
• dyspepsia
• vomiting
• belching

This medication should be stored in a tightly sealed container that is well-aired and kept at a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

White hexagonal tablet

Package unit

500 tablets/bottle, 30 tablets/bottle