Medication info
Alphedrine 25 mg Tablets (Orphenadrine Hydrochloride)

Alphedrine 25 mg Tablets (Orphenadrine Hydrochloride)

Prescription medicationTablet
Ingredient · strength
Orphenadrine Hydrochloride›25mg / 1 tablet
Manufacturer / importer
Samnam Pharmaceutical Co., Ltd.
Appearance
Light yellow round tablet
Packaging
500 tablets/bottle
Approval status
Active

MFDS item code 199701555 · Notified 1997.03.31 · Insurance code 653701100

Summary

Main use
Treatment of parkinsonism (e.g., idiopathic or postencephalitic); relief of pain from skeletal muscle spasms
Who uses it
Adults
Adult dosage
(Oral: tablets) Adults: Administer 50㎎ of olpadrine hydrochloride orally 3 times daily. Adjust the dose appropriately according to age and symptoms. (Injection) Adults: Administer 80-120㎎ (4-6㎖) of olpadrine hydrochloride daily by intramuscular injection. Adjust the dose appropriately according to age and symptoms.

Ingredients

Manufacturer
Samnam Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of parkinsonism (e.g., idiopathic or postencephalitic); relief of pain from skeletal muscle spasms

  • Idiopathic Parkinson's disease
  • other types of Parkinson's disease
  • skeletal muscle spasms
View approved original text

This medication is used for idiopathic Parkinson's disease and other types of Parkinson's disease occurring after encephalitis or atherosclerosis. It is also effective for relieving pain caused by skeletal muscle spasms. Therefore, it helps improve motor function disorders associated with Parkinson's disease and reduce discomfort caused by muscle cramps.

Dosage and Administration

Adult dosage

(Oral: tablets) Adults: Administer 50㎎ of olpadrine hydrochloride orally 3 times daily. Adjust the dose appropriately according to age and symptoms. (Injection) Adults: Administer 80-120㎎ (4-6㎖) of olpadrine hydrochloride daily by intramuscular injection. Adjust the dose appropriately according to age and symptoms.

Precautions

This medication should not be used in patients with glaucoma. Patients with obstruction of the pylorus or duodenum should also not take this medication. It should not be administered to patients with obstructive peptic ulcers. Those with benign prostatic hyperplasia or bladder neck obstruction should also avoid this medication. This medication is not suitable for patients with esophageal motility disorders such as esophageal spasm or achalasia. Patients with myasthenia gravis should refrain from using this medication. Individuals with an allergic reaction to this medication should not use it. Additionally, since this medication contains lactose, patients with lactose intolerance or certain genetic metabolic disorders should not take it. Patients with tachycardia or cardiovascular diseases should exercise caution when using this medication. Patients with liver or kidney dysfunction should also use this medication with care. Taking this medication may cause symptoms such as dry mouth, palpitations, constipation, urinary difficulties, blurred vision, nausea, vomiting, drowsiness, headaches, dizziness, and skin rashes. Most of these symptoms will resolve by reducing the dosage or discontinuing the medication. This medication can lead to drug dependence, so it should not be abruptly discontinued; instead, it should be gradually reduced under the guidance of a physician. For pregnant or breastfeeding women, the safety of this medication has not been sufficiently established, so it should only be used after consulting a physician, and only when necessary. In the case of children or infants, safety has also not been established, so it should be used cautiously and only when necessary.

Side effects

  • dry mouth
  • palpitations
  • constipation
  • dysuria
  • blurred vision
  • colic
  • drowsiness
  • muscle tension
  • nausea
  • vomiting
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  • weakness
  • headache
  • tachycardia
  • dizziness
  • rash
  • skin disorders
  • hypersensitivity
  • insomnia
  • irritability

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a tightly sealed container that blocks light. Additionally, it is best to avoid extremely hot or cold environments and store the medication at room temperature, between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Light yellow round tablet

Package unit

500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.