Rokpen Tablet (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2 ○ Adult: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For single dose therapy, administer 60-120 mg orally. 2. For indication 3 ○ Adult: Administer 60 mg of loxoprofen sodium (anhydrous) orally. Typically, it can be administered twice a day, with a maximum of 180 mg per day. It is advisable to take it on an empty stomach.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages per day; therefore, consultation with a physician or pharmacist is essential. It may increase the risk of cardiovascular disease, which necessitates special caution for individuals with heart conditions or risk factors, and such individuals should immediately inform healthcare professionals if cardiovascular symptoms appear. Serious gastrointestinal issues such as gastrointestinal bleeding, ulcers, and perforation may occur, so those with a history of gastrointestinal disease or the elderly should use this medication with extra caution. Patients with peptic ulcers, severe liver or kidney dysfunction, severe heart failure, known drug allergies, pregnant women in late pregnancy, and nursing mothers should not take this medication. Individuals with a history of peptic ulcers or blood disorders, liver or kidney disease, hypertension, asthma, the elderly, or women in early or mid-pregnancy should use this medication carefully. If any hypersensitivity reactions such as rash, itching, hives, difficulty breathing, or low blood pressure occur during use, discontinue use immediately and consult a healthcare professional. If gastrointestinal symptoms such as bleeding, abdominal pain, nausea, vomiting, or diarrhea occur, stop taking the medication and seek treatment, as severe cases may lead to shock. Various adverse reactions such as drowsiness, dizziness, headache, anemia, liver dysfunction, kidney dysfunction, and skin rash may occur, so careful monitoring of the patient's condition is essential. It is advisable not to take this medication concurrently with other non-steroidal anti-inflammatory drugs, and inform your healthcare provider of any medications you are currently taking, as interactions may occur. Particularly in late pregnancy, it may pose risks to the fetus, and use during breastfeeding is also best avoided. Safety in children has not been established, so caution is required, and the risk of side effects is higher in the elderly, necessitating careful use. This medication should be taken at the minimum effective dose for the shortest duration possible, with regular blood tests and liver and kidney function tests to check for abnormalities.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue throughout the body, sudden and severe headache, lightning-like headache, seizures, confused consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• gastric discomfort
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly sealed container to prevent air ingress and kept at a temperature between 1 and 30 degrees Celsius (34 to 86 degrees Fahrenheit) to maintain its efficacy and safety.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle