Summary
- Main use
- Treatment of rheumatic and collagen diseases, and disorders of the skin, allergies, lungs, eyes, blood, intestines, liver, and kidneys
- Who takes it
- Adults · Children
- Adult dose
- Administer 6-90mg of deflazacort (micronized) orally per day.
- Child dose
- Adjust the dose according to the disease. Adjust the dose as appropriate according to age and symptoms.
Ingredients
- Manufacturer
- Handok Co., Ltd.
Efficacy & effects
Treatment of rheumatic and collagen diseases, and disorders of the skin, allergies, lungs, eyes, blood, intestines, liver, and kidneys
- Rheumatological disorders
- collagen diseases
- psoriatic arthritis
- rheumatoid arthritis
- rheumatic polymyalgia
- acute rheumatic fever
- systemic lupus erythematosus
- dermatomyositis
- giant cell arteritis
- Wegener's granulomatosis
- pemphigus
- bullous pemphigoid
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This medication is used in the treatment of various rheumatological diseases, including psoriatic arthritis, rheumatoid arthritis, and acute rheumatic fever, where effects have not been seen in collagen diseases. It is also beneficial for various skin diseases such as pemphigus and psoriasis, as well as allergic diseases like bronchial asthma. Additionally, it is utilized in the treatment of respiratory diseases like lung infiltration, ocular diseases such as choroiditis, and hematological disorders such as idiopathic thrombocytopenic purpura. It is effective for gastrointestinal conditions like ulcerative colitis and Crohn's disease, chronic active hepatitis, and kidney diseases such as nephrotic syndrome. Thus, it is widely used across various autoimmune and inflammatory diseases to alleviate symptoms and improve disease progression.
How to take
Adult dose
Administer 6-90mg of deflazacort (micronized) orally per day.
Child dose
Adjust the dose according to the disease. Adjust the dose as appropriate according to age and symptoms.
Precautions
This medication should generally not be used in patients with peptic ulcers. This medication suppresses immune function, which may worsen infections in patients with viral, bacterial, or fungal infections. It should also be avoided in patients with certain infectious diseases such as chickenpox, herpes zoster, and tuberculosis. Patients with hypersensitivity to this drug or genetic issues such as lactose intolerance should not use it. Diabetic patients should use it cautiously as it may increase blood sugar levels, and patients with severe myasthenia gravis should be careful as their symptoms may worsen. Patients with gastritis, esophagitis, osteoporosis, psychiatric disorders, or glaucoma should also be cautious as their conditions may deteriorate with this drug. Patients with heart disease, hypertension, or thromboembolic disease may experience worsening symptoms due to sodium and water retention and will require management. Long-term use may result in various side effects such as adrenal insufficiency, increased infection risks, osteoporosis, muscle weakness, neurological changes, and skin alterations. In particular, when discontinuing the medication, one should avoid abrupt cessation and taper off gradually; if withdrawal symptoms appear, one should consult a physician immediately. This medication should not be used with live vaccines, and close monitoring is required in the presence of infections. Additionally, it may interact with multiple drugs, so inform the healthcare provider if taking other medications. During pregnancy, it should only be used when necessary due to potential impacts on the fetus, and breastfeeding should be avoided while using this drug. In children and the elderly, there is a higher risk of growth delays or infection, so caution should be taken.
Side effects
Weight gain, suppression of hypothalamic-pituitary-adrenal axis, exogenous Cushing's syndrome, moon facies, hirsutism, menstrual irregularities and amenorrhea, diabetes, steroid withdrawal syndrome, acute adrenal insufficiency after treatment cessation, growth disorders in children, increased demand for diabetes treatment due to impaired glucose tolerance, pheochromocytoma crisis, increased intraocular pressure, glaucoma, posterior subcapsular cataract, secondary eye infections due to fungi or viruses, central serous chorioretinopathy, retinal disorders, exophthalmos, optic disc edema, blurred vision, dyspepsia, peptic ulcer, bleeding, nausea, perforation of peptic ulcer, acute pancreatitis, candidiasis, edema, allergic reactions, leukocytosis, increased susceptibility to infections, masking of infections, precipitated infections, relapse of latent tuberculosis, changes in fluid and electrolyte balance, hypokalemia, increased appetite, tumor lysis syndrome, pathological fractures, muscle wasting, avascular necrosis, myopathy, tendinitis, tendon rupture, myasthenia, osteoporosis, aseptic necrosis of the femoral and humeral heads, spinal compression fractures, headaches, dizziness, sleep disturbances, mood changes, depression, neurosensitivity, confusion, brain tumors, insomnia, abnormal dreams, crying, emotional disturbances, unusual behavior, euphoria, restlessness, hypomania, anxiety, agitation, neurosis, disorientation, psychosis, hallucinations, psychological dependence, exacerbation of epilepsy, cognitive impairment, amnesia, acne, striae, fragile skin, thin skin, scars, delayed wound healing, contusions, capillary dilation, skin atrophy, petechiae, purpura, toxic epidermal necrolysis, Stevens-Johnson syndrome, abrasions, thrombosis, hypertrophic cardiomyopathy, hypertension, sodium and fluid retention, heart failure, potassium depletion, hypokalemic alkalosis, protein and calcium imbalance
Not everyone experiences these, and they can vary from person to person.
Storage
The medication should be stored in a tightly sealed container to prevent air and moisture from entering. This will help maintain its efficacy for a long time and prevent degradation.
Appearance and packaging
Appearance
It is a white, round tablet.
Package unit
100 tablets (10 tablets/PTP X 10)
Questions about this medicine
No questions yet.
For anything that needs medical judgment, consult a doctor or pharmacist.
