Apental Tablet (Aceclofenac)

Adult dose

As acyclofenac, take 100 mg twice daily, every 12 hours. This medication should be taken whole without chewing or crushing. Adjust the dose appropriately based on symptoms. To minimize cardiovascular adverse reactions from this medication, it should be given at the lowest effective dose for the shortest duration.

Patients who regularly consume more than three glasses of alcohol per day should consult their doctor or pharmacist before taking this medication. Drinking alcohol frequently while taking this medication may increase the risk of gastrointestinal bleeding. This drug may increase the risk of cardiovascular and cerebrovascular diseases, so those with risk factors for heart diseases or cerebrovascular diseases should use it with caution. The longer and higher the dosage, the greater the cardiovascular risk may be, thus it is important to use the minimum effective dose for the shortest possible duration. Additionally, during treatment, it is essential to monitor for any cardiovascular symptoms in consultation with a physician. This drug can cause severe gastrointestinal side effects such as gastrointestinal bleeding, ulcers, and perforation, especially in the elderly or those with a history of gastrointestinal diseases. If gastrointestinal symptoms occur, it is crucial to consult healthcare professionals promptly for appropriate action. Individuals with active peptic ulcers or bleeding, or with a history of such conditions, those who are hypersensitive to this drug or similar drugs, individuals with a history of asthma or allergic reactions should not take this medication. Also, those with heart failure, severe renal or liver impairment, and pregnant women in late pregnancy or breastfeeding should avoid this drug. People with renal or liver dysfunction, elderly patients, patients with heart failure, and patients with hypertension should use this medication with extra caution and may require regular testing as needed. This drug may cause various side effects such as dizziness, indigestion, elevated liver enzymes, skin rash, skin adverse reactions, anemia, leukopenia, thrombocytopenia, neutropenia, hemolytic anemia, aplastic anemia, agranulocytosis, hyperkalemia, depression, unusual dreams, insomnia, visual disturbances, optic neuritis, sensory disturbances, tremors, drowsiness, headaches, taste disorders, neck stiffness, fever, orientation disturbances, confusion, hallucinations, tinnitus, lethargy, palpitations, flushing, high blood pressure, and heart failure. It is important to inform healthcare providers immediately if any abnormal symptoms occur. Caution should be exercised during tasks requiring concentration such as driving or operating machinery, as dizziness or drowsiness may occur. Pregnant women, especially in the late stages, should consult their physician before taking this medication due to potential effects on the fetus. If taking other medications, interactions may occur, so patients should inform their doctor or pharmacist about any currently used medicines. The safety and efficacy of this medication in children have not been established, so it is advisable not to use it in pediatric or adolescent populations. Elderly patients have a higher risk of side effects like gastrointestinal bleeding and should take this medication with particular caution. Lastly, in the case of an overdose, symptoms may include gastrointestinal irritation, low blood pressure, respiratory depression, and seizures, requiring immediate medical attention for appropriate treatment.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rashes with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty in breathing, asthma attack, breathing difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, and decreased urine output.

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• skin adverse reactions
• anemia
• leukopenia
• thrombocytopenia
• neutropenia
• hemolytic anemia

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius. This will help to preserve the medication's effectiveness and safety for a longer period.

Appearance

White round film-coated tablet (Export: orange round film-coated tablet)

Package unit

30 tablets/bottle, 500 tablets/bottle