Zistol Tablets (Misoprostol)

Adult dose

1. Treatment of gastric and duodenal ulcers, and gastritis and gastric or duodenal ulcers caused by nonsteroidal anti-inflammatory drugs: Administer 1 tablet per dose (equivalent to 200㎍ of misoprostol per dose) orally 4 times daily for 4-8 weeks with meals and at bedtime. 2. Prevention of gastritis and gastric or duodenal ulcers caused by nonsteroidal anti-inflammatory drugs: Administer 2~4 tablets per day (equivalent to 400-800㎍ of misoprostol) orally in divided doses with meals and at bedtime. Administer this medicine during the period of nonsteroidal anti-inflammatory drug treatment as directed by a physician. To minimize diarrhea that may occur as an adverse effect, take this medicine with food and avoid concomitant use with magnesium-containing antacids. The dose may be increased or decreased as appropriate according to age and symptoms.

This medication should not be used in pregnant women as it could induce pregnancy or cause miscarriage, posing serious risks to the fetus. Women of childbearing age must confirm they are not pregnant before taking this medication and should use effective contraceptive methods. If pregnancy is confirmed while taking this medication, use should be discontinued immediately. This medication should not be administered to individuals with allergies to misoprostol or any other components, and it should be used cautiously in patients with blood pressure issues or liver disorders. Gastrointestinal symptoms such as diarrhea, abdominal pain, and nausea may occur during use, and if symptoms are severe, consultation with a healthcare professional is necessary. Additionally, rare allergic reactions such as skin rashes, headaches, dizziness, and breathing difficulties should be monitored. Exposure to this medication during pregnancy can result in congenital abnormalities or severe health issues for the fetus; therefore, pregnant women or those who may become pregnant should avoid use. Breastfeeding women should also refrain from using this medication as it may cause diarrhea or other side effects in the infant. Elderly patients or those with gastrointestinal disorders should be cautious when taking this medication to prevent worsening symptoms. In case of overdose, symptoms such as severe diarrhea, abdominal pain, hypotension, and uterine contractions may appear, requiring immediate medical attention. This medication should be stored in a safe place out of the reach of children and should not be transferred to another container. Additionally, it should only be used by the person to whom it was prescribed and must not be given to others.

• Shock
• anaphylaxis
• diarrhea
• abdominal pain
• nausea
• abdominal distension
• loss of appetite
• dyspepsia
• vomiting
• belching

This medication may be sensitive to air and moisture, so it should be stored in a tightly closed container. It should also be kept away from direct sunlight and stored at room temperature, avoiding extremes of heat or cold.

Appearance

White round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle