Medication info

Isopto Carpine 2% Eye Drops (Pilocarpine Hydrochloride)

Prescription medicationSolutionEye dropsApproval withdrawn
Ingredient · strength
Pilocarpine Hydrochloride›20mg / 1mL
Manufacturer / importer
Novartis Korea Ltd.
Appearance
Colorless solution
Packaging
15 mL/bottle
Approval status
Approval withdrawn

MFDS item code 199604917 · Notified 1996.07.31

This product's status changed to Approval withdrawn on 2024.09.30. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Induction of miosis for diagnostic and therapeutic purposes; treatment of glaucoma
Who applies the drops
Adults
Adult eye dose
(Eye drops) Instill 1-2 drops 3-5 times daily. Adjust the dose as needed according to symptoms. (Ophthalmic ointment) Apply a small amount (1.3cm) into the conjunctival sac once daily at bedtime. Adjust the dose as needed according to symptoms.

Ingredients

Importer
Novartis Korea Ltd.

Efficacy & effects

Induction of miosis for diagnostic and therapeutic purposes; treatment of glaucoma

  • Glaucoma
  • miosis
View approved original text

This medication is used to constrict the pupils for the diagnosis or treatment of glaucoma. This helps to control intraocular pressure and prevent damage to the optic nerve.

How to apply drops

Adult eye dose

(Eye drops) Instill 1-2 drops 3-5 times daily. Adjust the dose as needed according to symptoms. (Ophthalmic ointment) Apply a small amount (1.3cm) into the conjunctival sac once daily at bedtime. Adjust the dose as needed according to symptoms.

Precautions

It is very important that this medication not be used in certain patients. For example, individuals who are allergic to the active ingredient or any components of this medication should not use it. Additionally, patients with iritis, anterior uveitis, malignant glaucoma, pupillary block glaucoma, and corneal damage should not use this medication. This medication should be used cautiously in patients with bronchial asthma, heart disease, hyperthyroidism, gastrointestinal obstruction, or Parkinson's disease. Particular caution is also needed for children, individuals with myopia, or patients with hypertension or hypotension. Various adverse eye reactions may occur during use. For example, symptoms may include eye pain, blurred vision, itching, and redness, and rarely systemic symptoms such as headaches, vomiting, or bronchospasms may occur. This medication may affect vision when driving or operating machinery, so caution is advised. Additionally, if you are wearing soft contact lenses, you should remove them before administering the drops and wait at least 15 minutes after administration before reinserting them. It is recommended that pregnant or nursing women avoid using this medication, particularly women who may become pregnant should avoid it due to the risk of uterine contractions. In the case of overdose, inducing vomiting or gastric lavage may be necessary, and symptoms such as increased salivation, sweating, tearing, nausea, or vomiting should be closely monitored. When using the medication, proper instillation methods should be followed, ensuring that the tip of the container does not come in direct contact with the eye. Additionally, it is advised not to use the medication for more than one month after opening and to store it in a cool place away from direct sunlight. This medication may interact with other drugs; therefore, when using it with muscle relaxants, cardiac glycosides, or anesthetics, it is essential to consult a healthcare professional.

Side effects

  • Ciliary spasm
  • blurred vision
  • itching
  • burning sensation
  • heat sensation
  • increased eyelid sensitivity
  • conjunctival congestion
  • temporary myopia
  • lens changes
  • decreased vision in dark places
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  • increased pupillary blockage
  • vitreous hemorrhage
  • retinal detachment
  • headache
  • eyebrow pain
  • sweating
  • increased salivation
  • tear secretion
  • nausea
  • vomiting
  • constipation
  • proptosis
  • bronchospasm
  • pulmonary edema
  • blood pressure changes
  • changes in heart rhythm
  • dizziness
  • decreased vision
  • eye pain
  • photophobia
  • floaters
  • eye irritation
  • eye congestion
  • retinal tear
  • eyelid swelling
  • miosis
  • vitreous detachment
  • glare
  • watery eyes
  • increased intraocular pressure
  • corneal edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Moreover, when storing the medication, it is best kept at room temperature, not too hot or too cold.

Appearance and packaging

Appearance

Colorless solution

Package unit

15 mL/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.