Rivoteran Tablets 150 mg (Ranitidine Hydrochloride)

Adult dose

As ranitidine, 150 mg should be taken orally twice a day, in the morning and at bedtime. For gastric and duodenal ulcers, 150 mg can be taken orally twice daily or 300 mg once daily at bedtime. Patients with duodenal ulcers can take 300 mg orally twice daily, in the morning and at bedtime. Patients with recurrent ulcers can take 150 mg once daily at bedtime as maintenance therapy.

Child dose

Children aged 8 to 18 years can be administered 150 mg (2 mg per kg of body weight) once, up to twice a day.

This medicine should not be used in certain patients. For example, patients with a history of allergy to this drug or its components, or a history of acute porphyria should not take this drug. Additionally, this drug contains lactose, so those with genetic diseases leading to lactose intolerance should not take it. Patients with poor kidney function may have elevated blood concentrations due to insufficient elimination of the drug from the body and should have their dosage reduced or intervals between doses extended. Caution is also necessary for patients with impaired liver function. Patients with a history of drug allergies, elderly patients, and those taking nonsteroidal anti-inflammatory drugs should use this drug cautiously, and especially if there is a history of gastric ulcers, regular examination is necessary. This drug can mask the symptoms of gastric cancer, so patients with gastric ulcers or new or changing dyspeptic symptoms in middle-aged individuals should confirm whether cancer is present before taking this medication. Patients with gastric and duodenal ulcers infected with Helicobacter pylori should also receive treatment to eradicate the bacteria. While taking this medication, very rarely severe allergic reactions such as anaphylactic shock may occur, so if symptoms arise, take the medication immediately and go to the hospital. If symptoms of hypersensitivity such as hives, rash, fever, or breathing difficulties appear, take the medication again immediately. Abnormalities may appear in blood tests such as a decrease in white blood cells or platelets, so if symptoms such as fatigue, bleeding, or fever occur, tests should be conducted, and if necessary, the medication should be discontinued. Symptoms indicating liver dysfunction can occur very rarely; if jaundice or severe fatigue occurs, consult a doctor promptly. Clinical signs of heart rhythm disturbances, constipation, nausea, abdominal pain, confusion, and dizziness can occur very rarely, so careful observation is needed if symptoms develop. This drug can cause various side effects, such as myalgia, arthralgia, and skin rash, so any unusual symptoms should be reported to healthcare professionals immediately. During treatment, the progression of the disease should be closely monitored, and if there is no effect, it is advisable to change to another treatment method. Particularly, special caution should be taken with elderly patients, chronic lung disease patients, diabetes patients, and immunocompromised patients as they may have a higher risk of developing pneumonia. If dizziness or drowsiness occurs after taking this medication, driving or operating dangerous machinery should be avoided. When taking this medication with other drugs, there may be drug interactions, so consult a doctor or pharmacist. Pregnant women or those who may become pregnant should only use this medication when its potential effects on the fetus are fully determined, and only if necessary. Lactating women should also use this medication only when necessary, as it can be transmitted through breast milk. Safety for children has not been sufficiently confirmed, so it should be used cautiously in the pediatric population. Elderly patients may have reduced kidney function, so dosage and intervals should be adjusted accordingly. Some urine tests may yield false-positive results when taking this medication, so care should be taken with testing methods. In cases of overdose, treatment such as vomiting or gastric lavage may be necessary, and in severe cases, blood dialysis can be used to remove the drug. This drug should be kept out of reach of children, and transferring it to another container is not good for maintaining quality. If taken for a prolonged period, it may affect the eyes, so it is advisable to have ophthalmologic check-ups while taking it.

Serious side effects

Anaphylactic shock, hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, liver dysfunction (jaundice

Mild side effects

Hives, angioedema, rash, fever, bronchospasm, hypotension, chest pain, granulocytopenia, elevated serum creatinine levels, leukopenia, thrombocytopenia, aplastic anemia, agranulocytosis, aplastic anemia, acquired immune hemolytic anemia, eosinophilia, temporary and reversible liver dysfunction (elevated levels of AST, ALT, γ-GTP, ALP), bradycardia, atrioventricular block, tachycardia, vasculitis,

This medication is sensitive to light, so it should be stored in a container that blocks light. Additionally, it is best to store the medication at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the effectiveness and safety of the medication.

Appearance

Round film-coated tablet, pale yellow to pale beige

Package unit

30 tablets/bottle, 100 tablets/bottle