Troll Injection (Tramadol Hydrochloride)

Adult administration

As Tramadol Hydrochloride, administer 50-100mg by intravenous or intramuscular injection, then repeat every 4-5 hours as needed. The maximum daily dose can be up to 400mg.

This medication may cause seizures if taken beyond the recommended dosage, so the prescribed dosage must be strictly adhered to. This medication should be used with caution in patients at risk for seizures, and individuals with epilepsy or a history of seizures should consult a physician before administration. Long-term use may lead to mental or physical dependence; therefore, patients with a history of substance abuse should be particularly cautious, and short-term use is recommended. Concomitant use of this medication with alcohol or central nervous system depressants can lead to severe sedation, respiratory depression, coma, or death, thus it should be avoided or used under strict medical supervision. Individuals genetically metabolizing this medication quickly may experience increased serum levels of active metabolite, raising the risk of respiratory depression; therefore, dosage adjustment and monitoring of symptoms are necessary in such cases. This medication should not be used in pediatric patients under 12 years of age or in those under 18 who have undergone tonsillectomy or adenoidectomy, and it is advisable to avoid administration in adolescents aged 12 to 18 with specific risk factors. When using ampoule forms of injection, care must be taken to cut them carefully to avoid glass shard contamination, and special attention is required when administering to children or the elderly. This medication should not be administered to patients with certain conditions, such as acute alcohol intoxication, severe respiratory depression, head injuries, severe kidney or liver impairments, pregnant and nursing women, and those taking specific medications. Patients may experience drowsiness or dizziness upon administration, so it is advisable to avoid driving or operating hazardous machinery and to refrain from using this medication for minor pain. In case of overdose, serious respiratory depression and seizures may occur, requiring immediate emergency response, and naloxone may be used as an antidote. This medication may interact with several drugs; therefore, it is essential to consult with a physician or pharmacist when taking other medications, particularly avoiding the combination with central nervous system depressants, antidepressants, and MAO inhibitors. Pregnant or nursing women should not take this medication, as it may transfer to the baby through breast milk and pose risks. Elderly patients (over 75 years old) may have increased blood levels of this medication, so dosage should be adjusted accordingly. If any psychiatric reactions, hypersensitivity, respiratory difficulties, or other symptoms occur during treatment, inform the medical staff immediately.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, severe allergic reactions, respiratory depression, dyspnea, exacerbation of asthma, severe skin reactions (Stevens-Johnson syndrome), facial pallor, severe rash, blisters, skin peeling, pain in oral/ocular mucous membranes, severe edema, seizures, convulsions, confusion, severe headache, paralysis, lightning headache, visual disturbances, liver abnormalities (jaundice), yellowing of the skin or eyes, jaundice, hypertension.

Mild side effects

• Headache
• dizziness
• drowsiness
• fatigue
• lethargy
• nausea
• vomiting
• constipation
• decreased appetite
• sweating

This medication should be stored in a sealed container to prevent air or moisture ingress and should preferably be kept at room temperature. It is important to avoid very hot or cold places and to store it in a cool place away from direct sunlight.

Appearance

A colorless, odorless, transparent liquid contained in a colorless and transparent ampoule.

Package unit

[Domestic] 1ml × 50 ampoules [Export] 2ml × 50 ampoules