Espenac Injection (Diclofenac Sodium)

Adult dosage

Oral: As Diclofenac Sodium, the initial dose is 100-150 mg per day, and in cases of relief or long-term use, 75-100 mg per day in 2-3 divided oral doses. Injection: Administer 75 mg (1 ampoule) deeply intramuscularly in one side of the upper buttock once daily. In severe cases, 75 mg can be administered twice daily, alternating between both buttocks. Sustained-release preparation: Administer 100 mg once daily.

Children's dosage

Administer 0.5-3 mg per kg of body weight in 2-3 divided oral doses per day. Adjust according to age, condition, and symptoms.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three glasses of alcohol daily; it is essential to consult a doctor or pharmacist. Individuals with cardiovascular diseases or risk factors need to be cautious as this medication may cause severe cardiovascular issues such as myocardial infarction or stroke. This medication can lead to serious adverse reactions such as gastrointestinal bleeding, ulcers, or perforation, particularly in seniors or those with a history of gastrointestinal diseases. In cases of severe allergic reactions, Kounis syndrome, a serious allergic symptom that can provoke myocardial infarction, may occur, necessitating immediate consultation with medical personnel if symptoms appear. When using this injectable ampoule, care should be taken to avoid the risk of glass particle contamination, especially in children and the elderly. Individuals with peptic ulcers, severe liver or kidney diseases, severe hypertension, heart failure, or hypersensitivity to any components of this drug should not take it. During treatment, regular blood tests and liver and kidney function tests should be conducted, and any abnormal symptoms should be reported immediately. This medication should be avoided by pregnant women, especially in late pregnancy, as it may be harmful to the fetus. Additionally, breastfeeding mothers should be cautious, as the drug can be passed into the breast milk and affect the baby. Children and the elderly should use this medication at the minimal effective dose with appropriate caution and be vigilant for any adverse reactions. The risk of adverse reactions may increase when this medication is taken in conjunction with other nonsteroidal anti-inflammatory drugs or specific medications, so it is crucial to inform a doctor or pharmacist of any concurrently used medications. In the event of an overdose, symptoms such as hypotension, renal failure, convulsions, gastrointestinal disturbances, and respiratory depression may occur, requiring immediate medical assistance.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), systemic lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Peptic ulcers
• gastrointestinal bleeding
• esophageal ulcers
• perforation
• granulocytopenia
• hemoglobin decrease
• leukopenia
• thrombocytopenia
• anemia
• aplastic anemia

This medication should be stored in a light-blocking container and kept at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the efficacy of the drug and prevents deterioration.

Appearance

Brown ampoule filled with a colorless or yellowish liquid

Package unit

2 milliliters x 50 ampoules