Isotane Tablet (Topisofam)

Adult dose

Administer tofisopam 50 mg per dose orally, 3 times daily. Adjust the dose as appropriate according to symptoms.

This medication contains lactose, and patients with genetic conditions that prevent the digestion of lactose should not use it. Those with acute angle-closure glaucoma, myasthenia gravis, structural issues in the brain, moderate or severe respiratory failure, and older adults should use this medication cautiously. Taking this medication may result in neurological symptoms such as drowsiness, dizziness, headache, and insomnia, as well as gastrointestinal issues like nausea or constipation. If allergic reactions like rash or itching occur, one should stop taking the drug immediately. This medication may affect liver function, potentially leading to elevated liver enzymes. During treatment, drowsiness or decreased concentration may occur, so driving or operating hazardous machinery should be avoided. Taking with other central nervous system depressants or alcohol may enhance effects, so caution is advised. When used with certain immunosuppressants, drug concentrations may change, requiring monitoring. Women in early pregnancy or those who may become pregnant should carefully consider the benefits and risks when using this medication, and in late pregnancy, there may be side effects for the newborn, so greater caution is warranted. Breastfeeding women should avoid taking this medication if possible, as it may pass into breast milk, and if it must be taken, discontinuation of breastfeeding is recommended. Safety in children has not been thoroughly established, so caution should be used for this group. Older adults may have reduced body function, necessitating special attention such as dose reduction. In case of overdose, professional detoxification may be necessary, so contact a medical institution immediately. Store this medication out of the reach of children in a cool, dry place, avoiding direct sunlight, and do not transfer it to another container.

• drowsiness
• staggering
• dizziness
• headache
• insomnia
• anxiety
• agitation
• depression
• tremors
• numbness

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture, at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will help maintain the drug's effectiveness.

Appearance

Round tablets, white to off-white

Package unit

60 tablets (10 tablets in PTP packaging × 6), 500 tablets per bottle