Kinpoine Injection (Diclofenac Sodium)

Adult dosage

(Oral) The initial dose of diclofenac sodium is 100-150mg per day, and in cases of relief or long-term administration, it is administered as 75-100mg per day divided into 2-3 doses. (Injection) For diclofenac sodium, 75mg (1 ampule) is deeply intramuscularly injected into one side of the upper buttock once a day. In severe cases, it may be administered as 75mg (1 ampule) twice a day, alternating both sides of the buttock.

Children's dosage

Administer orally in 2-3 divided doses of 0.5-3mg per kg of body weight per day, adjusting appropriately according to age, disease, and symptoms.

This medication should be consulted with a doctor or pharmacist before taking, especially for those who drink more than three glasses of alcohol daily, as they are at a higher risk of gastrointestinal bleeding when taking this medication. This medication can affect the cardiovascular system, potentially increasing the risk of severe cardiovascular conditions such as myocardial infarction or stroke. Special caution is required for patients with a history of cardiovascular disease or risk factors. It may place strain on the gastrointestinal tract and can cause severe gastrointestinal disorders such as gastric ulcers, bleeding, or perforation. Elderly patients or those with a history of gastrointestinal diseases must be particularly careful, and if gastrointestinal bleeding occurs during use, they should consult medical personnel immediately. In the case of severe allergic reactions, it can cause Kounis syndrome, a rare allergic symptom that can trigger myocardial infarction; thus, immediate medical attention is required for symptoms such as chest pain. The injectable form of this medication may contain glass fragments, so care must be taken during use, particularly for children and the elderly. Patients with serious conditions such as peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, hypertension, or heart failure should not take this medication. Those who have had allergic reactions to asthma or non-steroidal anti-inflammatory drugs (NSAIDs) may also be at risk when taking this medication. This medication can have severe effects on the fetus towards the end of pregnancy, so it should be avoided, particularly in the late stages of pregnancy. While breastfeeding, this medication can be transmitted through breast milk and may be harmful to the baby; thus, it is advisable to either discontinue breastfeeding or stop the medication. Elderly patients and children should use the minimum effective dose cautiously and notify healthcare professionals if any adverse reactions occur. Taking this medication in conjunction with other NSAIDs could increase the risk of side effects, so concurrent use is not recommended. Regular check-ups for blood pressure, liver function, and kidney function are necessary while taking this medication, and if any adverse symptoms appear, the medication should be stopped immediately, and a doctor should be consulted.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness → severe allergic reactions.
• Severe rash with high fever, blisters, skin peeling, painful mucous membranes in the mouth/eyes → severe skin reactions.
• Shortness of breath or difficulty breathing, asthma attack, cough accompanied by fever → breathing problems.
• Yellowing of the skin or eyes (jaundice), extreme drowsiness → liver dysfunction (jaundice).

Mild side effects

• Hives
• rash
• itching
• eczema
• dermatitis
• angioedema
• erythema multiforme
• flushing
• exudative dermatitis
• photosensitivity

This medication may be sensitive to light, so it should be stored in an opaque container that does not allow light in. It should also be kept in a sealed container to prevent contact with air, preserving its efficacy.

Appearance

A colorless and transparent solution filled in a brown ampule for injection.

Package unit

For domestic use - 50 ampules/box [2mL/ampule]