Medication info

Talimepin Tablet (Talniflumate)

Prescription medicationTabletOralExpired
Ingredient · strength
Talniflumate›370mg / 1 tablet
Manufacturer / importer
Samnam Pharmaceutical Co., Ltd.
Appearance
Orange round film-coated tablets
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Expired

MFDS item code 199501100 · Notified 1995.06.07

This product's status changed to Expired on 2024.04.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of arthritis (rheumatoid arthritis, etc.)
Who takes it
Adults
Adult dose
Administer 370 mg of talniflumate per dose orally 3 times daily. For severe cases, administer 740 mg per dose. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Samnam Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of arthritis (rheumatoid arthritis, etc.)

  • Rheumatoid arthritis
  • osteoarthritis
View approved original text

This medication is primarily used for the treatment of rheumatoid arthritis and osteoarthritis (degenerative arthritis). It helps reduce inflammation and pain in rheumatoid arthritis, and improves pain and movement limitations associated with osteoarthritis due to joint degeneration. This drug is effective in restoring joint function and alleviating symptoms in both conditions.

How to take

Adult dose

Administer 370 mg of talniflumate per dose orally 3 times daily. For severe cases, administer 740 mg per dose. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication may cause serious side effects such as gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages daily, and should be used with caution in such cases in consultation with a doctor or pharmacist. This drug can affect the cardiovascular system, increasing the risk of conditions like myocardial infarction or stroke; therefore, patients with cardiovascular diseases or risk factors should exercise extra caution. Patients should closely monitor for cardiovascular symptoms while taking this medication and immediately inform healthcare professionals if symptoms occur. This medication carries the risk of serious gastrointestinal issues such as bleeding, ulceration, and perforation, making it particularly important for elderly patients or those with a history of gastrointestinal disease to use it cautiously. Long-term use increases the likelihood of gastrointestinal adverse reactions, and any indication of gastrointestinal bleeding during treatment warrants immediate medical attention. Patients with peptic ulcers or hypersensitivity to this medication, as well as those allergic to aspirin or other non-steroidal anti-inflammatory drugs, should not take this medication. Patients with severe liver, kidney, or heart impairments, as well as pregnant or nursing women, should avoid using this medication for safety reasons. Patients with mild to moderate liver, kidney, or heart conditions or the elderly, as well as those taking diuretics, must use this medication carefully and have their conditions frequently monitored. While taking this medication, patients should be vigilant for gastrointestinal symptoms such as nausea, vomiting, diarrhea, abdominal pain, as well as hypersensitivity reactions like skin rashes, itching, and difficulty breathing. Cardiovascular symptoms such as elevated blood pressure, arrhythmias, and chest pain may occur; if any abnormal symptoms arise, healthcare professionals should be notified. This medication can cause severe skin reactions; if rashes or blisters appear, stop taking it immediately and consult a doctor. Long-term use of this medication may affect liver or kidney function, necessitating regular evaluations, and if any unusual findings are noted, discontinuation of the medication is required. Patients with aspirin-sensitive asthma should avoid this medication as it may cause severe bronchospasms, and asthma patients should use it cautiously. The risk of adverse effects may increase when used in conjunction with other anti-inflammatory medications, so it is advisable to avoid co-administration. This medication may interact with ACE inhibitors, diuretics, lithium, methotrexate, anticoagulants, and other drugs, necessitating careful consideration and consultation with healthcare professionals for patients taking these medications. During pregnancy, particularly in late pregnancy, this medication may pose risks to the fetus, therefore it should not be taken, and nursing women should also exercise caution when using this medication. This medication should not be administered to children under 12 years old as it cannot be used safely in that age group. Elderly patients should take this medication at the minimum dose with careful monitoring for adverse reactions.

Side effects

  • Gastrointestinal bleeding
  • cardiovascular thrombotic reaction
  • myocardial infarction
  • stroke
  • nausea
  • vomiting
  • photosensitivity
  • asthma attack
  • generalized weakness due to hypotension
  • hypersensitivity shock
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  • diarrhea
  • abdominal distension
  • constipation
  • indigestion
  • ulcerative stomatitis
  • abdominal pain
  • hematemesis
  • colitis
  • exacerbation of Crohn's disease
  • increased blood pressure
  • tachycardia
  • chest pain
  • arrhythmia
  • palpitations
  • congestive heart failure
  • edema
  • hypertension
  • heart failure
  • vesicular reaction
  • Stevens-Johnson syndrome
  • Lyell's syndrome
  • rash
  • urticaria
  • itching
  • purpura
  • dizziness
  • acute renal failure
  • interstitial nephritis
  • nephrotic syndrome
  • fluoride toxicity
  • abnormal liver function tests
  • thrombocytopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air or moisture from entering. It is advisable to maintain room temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

Orange round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.