Ilseongisopting Sustained Release Tablets 240 mg (Verapamil Hydrochloride)

Adult dosage

(Oral: Tablets) Adults: Administer 40-80㎎ of verapamil hydrochloride orally per dose, 3 times daily. Adjust the dose as appropriate according to age and symptoms. (Oral: Extended-release tablets and capsules) Adults: As the initial dose, administer 180㎎ or 240㎎ of verapamil hydrochloride orally once daily with breakfast. If the effect is inadequate, the dose may be divided and administered twice daily (morning and evening) as prescribed by a physician, within the maximum daily dose of 480㎎. Adjust the dose as appropriate according to age and symptoms. (Injection) Adults: Administer 5-10㎎ of verapamil hydrochloride slowly by intravenous injection per dose. The dose may be repeated if necessary. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in patients with specific symptoms among those with heart diseases. For example, it should not be administered to patients with severely weakened heart function such as congestive heart failure, those with cardiac rhythm issues, patients with very low blood pressure, or women who are pregnant or likely to become pregnant. Additionally, caution is required for patients who have had allergies to this medication or are taking certain other medications. This drug should be used cautiously in patients with bradycardia, mild cardiac conduction disorders, or impaired liver or kidney function. In particular, patients with severely impaired liver function need to reduce the dosage, and those with diminished kidney function must be carefully monitored. Patients with neuromuscular diseases may also need dosage adjustments when using this medication. While taking this medication, symptoms like decreased heart rate or low blood pressure may occur, so regular electrocardiogram checks are necessary, and if any unusual signs appear, patients should consult their doctor immediately. Additionally, various side effects such as skin rashes, allergic symptoms, digestive disturbances, fatigue, breathlessness, etc., can occur, so caution is warranted. This drug can exacerbate symptoms if suddenly discontinued; therefore, do not stop taking it arbitrarily without medical guidance, and blood pressure and heart condition must be consistently monitored during treatment. This medication may interact with various other drugs; thus, if other medications are being taken, patients must inform their doctor or pharmacist. In particular, when taken with heart-related medications, antihypertensives, anticoagulants, sedatives, antibiotics, and antiviral medications, there may be changes in side effects or efficacy. Pregnant or breastfeeding women are advised not to take this medication, and safety and efficacy have not been established for children under 18. Elderly patients may experience more side effects due to decreased bodily functions, so caution is needed regarding dosage adjustments. In cases of overdose, severe hypotension, arrhythmias, or coma may occur; thus, it is critical to seek hospital treatment immediately, and since this drug is not removed by hemodialysis, long-term observation is needed. Finally, this medication may slow response times while driving or operating machinery, so extra caution is required, particularly after starting treatment, changing dosages, or when taken with alcohol.

pulmonary edema, atrioventricular block (1st, 2nd, 3rd degree), hypotension, sinus bradycardia, asystole, peripheral edema, tachycardia, palpitations, flushing, rash, constipation, nausea, vomiting, anorexia, intestinal obstruction, gingival swelling, abdominal pain, abdominal discomfort, allergic reactions, elevated AST, elevated ALT, increased serum prolactin, decreased serum luteinizing hormone, decreased serum testosterone concentration, fatigue, dyspnea, angina, atrioventricular dissociation, chest pain, claudication, myocardial infarction, purpura, syncope, diarrhea, thirst, gastrointestinal intolerance, petechial hemorrhage, contusion, cerebrovascular damage, confusion, balance disorders, insomnia, muscle cramps, psychiatric symptoms, drowsiness, headache, dizziness, sensory disturbances, agitation, tremor, arthralgia, rash, alopecia, hyperkeratosis, sweating, erythema multiforme, angioedema, macules, hives, mucous membrane syndrome, papular rash, pruritus, blurred vision, muscle weakness, myalgia, increased urination, spotty menstruation, gynecomastia, dribbling, erectile dysfunction, renal failure, vertigo, hyperkalemia, hypotension, severe atrioventricular block, bradycardia due to asystole, hyperglycemia, confusion, metabolic acidosis, acute respiratory distress syndrome

This medication can be sensitive to air and moisture; therefore, it is important to store it in a sealed container. The storage temperature should be maintained between 15 to 30 degrees Celsius and kept in a cool place away from direct sunlight.

Appearance

Sustained release film-coated pale green oval tablets.

Package unit

30 tablets/bottle, 250 tablets/bottle