Hwanydol 0.5 Microgram Soft Capsule (Alfacalcidol)

Adult dose

Chronic renal failure and osteoporosis: Administer Alphacalcidol at a dose of 0.5 to 1 µg orally once daily. Hypoparathyroidism and other diseases due to vitamin D metabolic disorders: Administer this medication at a dose of 1 to 4 µg orally once daily.

Child dose

Osteoporosis: Administer Alphacalcidol at a dose of 0.01 to 0.03 µg per kg body weight orally once daily. Other conditions: Administer this medication at a dose of 0.05 to 0.1 µg per kg body weight orally once daily.

This medication should not be taken by patients with hypercalcemia, hyperphosphatemia, or hypermagnesemia. It should also not be taken if the blood calcium and phosphate levels are too high or if the blood is alkaline. Individuals with symptoms of vitamin D toxicity or allergies to this medication or its components should avoid taking it. During treatment with this medication, it is advised not to take medications containing magnesium, vitamin D preparations, calcium supplements, or certain diuretics together. Breastfeeding women are recommended to avoid taking this medication as it may pass to the baby, or to discontinue breastfeeding while taking it. Pregnant women or those who may become pregnant should consult a physician before taking this medication to avoid potential harm to the fetus. Children, the elderly, or patients with a history of kidney stones or those currently taking specific medications should consult a specialist before using this medication. Adverse effects that may be observed during treatment include digestive disorders, neurological symptoms, heart issues, reduced kidney function, liver function abnormalities, skin rashes, eye problems, bone pain, and may require immediate consultation with a specialist if symptoms appear. Overdose of this medication can lead to severe hypercalcemia; therefore, regular testing of serum calcium levels and dosage adjustments are necessary. Calcium and phosphorus intake should be managed, dietary guidelines must be followed, and if abnormal symptoms occur, the medication should be stopped immediately and healthcare provider consulted. Store this medication out of reach of children, avoiding direct sunlight, in a cool, dry place in a tightly sealed container. Do not transfer to another container to prevent misuse.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain of mucous membranes in the mouth/eyes, breathlessness or difficulty breathing, asthma attacks, respiratory anomalies with cough + fever, yellowing of skin or eyes, profound lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness, vision problems, paralysis, significantly reduced urine output.

Mild side effects

• Loss of appetite
• nausea
• vomiting
• diarrhea
• constipation
• stomach pain
• discomfort in the stomach area
• abdominal bloating
• dyspepsia
• thirst

Drug interactions

This medication interacts with digoxin, resins such as cholestyramine, laxatives containing mineral oil, phenytoin, glucocorticoids, colesevelam, sucralfate, or antacids containing high levels of aluminum, estrogens (ethinyl estradiol, norethisterone), barbiturates, and anticonvulsants, so consultation with a physician or pharmacist is advised.

Food interactions

This medication interacts with magnesium-containing preparations, calcium-containing preparations, thiazide diuretics, and vitamin D and its derivatives.

This medication is sensitive to light and should be stored in a light-blocking container. Additionally, store it in a sealed container to avoid contact with air and maintain its efficacy.

Appearance

An oval-shaped soft capsule filled with a slightly viscous liquid that is light yellow to pale brown in color, enclosed in a transparent brown capsule.

Package unit

Bottle - 100 capsules/bottle, Bottle - 180 capsules/bottle, Bottle - 500 capsules/bottle, Bottle - 30 capsules/bottle, PTP - 120 capsules/box [(60 capsules (10 capsules/PTP×6)×2)], PTP - 30 capsules/box [(10 capsules/PTP×3) for export]