Medication info
Krimine Tablets (Talniflumate)

Krimine Tablets (Talniflumate)

Prescription medicationTabletOral
Ingredient · strength
Talniflumate›370mg / 1 tablet
Manufacturer / importer
Samjin Pharmaceutical Co., Ltd.
Appearance
Orange round film-coated tablet
Packaging
500 tablets/bottle, 30 tablets/bottle, 100 tablets/bottle, 100 tablets/box [10 tablets/ptp*10]
Approval status
Active

MFDS item code 199401132 · Notified 1994.10.05 · Insurance code 647802240

Summary

Main use
Treatment of arthritis (e.g., osteoarthritis)
Who takes it
Adults
Adult dose
Administer talniflumate 370 mg per dose orally 3 times daily. For severe cases, administer 740 mg per dose. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Samjin Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of arthritis (e.g., osteoarthritis)

  • Rheumatoid arthritis
  • osteoarthritis
  • degenerative arthritis
View approved original text

This medication is used for rheumatoid arthritis and osteoarthritis, that is, degenerative arthritis.

How to take

Adult dose

Administer talniflumate 370 mg per dose orally 3 times daily. For severe cases, administer 740 mg per dose. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three drinks a day; therefore, consultation with a doctor or pharmacist is necessary. Additionally, this drug can pose risks to the cardiovascular system and may increase the risk of severe cardiovascular diseases such as myocardial infarction or stroke. Individuals with a history of cardiovascular disease or those with risk factors should exercise caution and consult medical staff immediately if symptoms arise. This medication may cause serious adverse reactions such as gastrointestinal bleeding, ulcers, and perforation, especially in the elderly or those with a history of gastrointestinal diseases. It is essential to carefully monitor for gastrointestinal symptoms during the use of this medication and seek immediate treatment if any abnormal signs occur. Individuals with a history of peptic ulcers, allergies to any of the drug's ingredients, allergies to aspirin or other non-steroidal anti-inflammatory drugs, severe liver, kidney, or heart diseases, as well as pregnant or breastfeeding women should not take this medication. Caution should be exercised in individuals with mild liver or kidney dysfunction, those taking diuretics, the elderly, and those with allergies to certain pigment constituents when using this medication. While taking this medication, various adverse reactions such as nausea, vomiting, diarrhea, abdominal pain, skin rash, hives, dizziness, renal dysfunction, etc., may occur, thus symptoms must be carefully monitored. This medication should be used at the lowest possible dose and for the shortest period. If used for an extended period, regular blood tests and liver and kidney function tests should be conducted. Co-administration with other anti-inflammatory medications should be avoided, and since there may be interactions with certain medications, it is essential to inform medical staff of any other medications being taken. Particular caution is needed during late pregnancy as this medication may harm the fetus, and those who are breastfeeding should also exercise caution when taking it. This medication is not to be used in children, especially those under 12 years old, and special attention should be given to elderly patients to avoid adverse reactions. Finally, this medication should be kept out of reach of children and is best stored in its original container to avoid confusion.

Side effects

  • Nausea
  • vomiting
  • photosensitivity
  • asthma attacks
  • systemic fatigue due to hypotension
  • hypersensitivity shock
  • diarrhea
  • abdominal bloating
  • constipation
  • dyspepsia
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  • ulcerative stomatitis
  • abdominal pain
  • hematemesis
  • colitis
  • worsening of Crohn's disease
  • gastrointestinal bleeding
  • peptic ulcer
  • perforation
  • hypertension
  • tachycardia
  • chest pain
  • arrhythmia
  • palpitations
  • hypotension
  • congestive heart failure
  • edema
  • hypertension
  • heart failure
  • vesicular reactions
  • Stevens-Johnson syndrome
  • Riel syndrome
  • rash
  • hives
  • itching
  • purpura
  • dizziness
  • acute renal failure
  • interstitial nephritis
  • nephrotic syndrome
  • fluoride toxicity
  • abnormal liver tests
  • thrombocytopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. This will help maintain the medication's efficacy over time.

Appearance and packaging

Appearance

Orange round film-coated tablet

Package unit

500 tablets/bottle, 30 tablets/bottle, 100 tablets/bottle, 100 tablets/box [10 tablets/ptp*10]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.