Medication info
Liorufen Tablet 400 milligrams (Ibuprofen)

Liorufen Tablet 400 milligrams (Ibuprofen)

OTC medicationTablet경구
Ingredient · strength
Ibuprofen›400mg
Manufacturer / importer
알파제약(주)
Appearance
White elliptical tablet
Packaging
30 tablets - 30 tablets/PTP, 10 tablets - 10 tablets/PTP, 10 tablets - 10 tablets/strip
Approval status
Active

MFDS item code 199302515 · Notified 1993.05.04 · Insurance code 654200080

Summary

Main use
Improvement of symptoms related to arthritis such as rheumatoid arthritis and osteoarthritis
Who takes it
Adults · Children
Adult dose
Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, soft tissue injuries, non-joint rheumatic diseases, acute gout, psoriatic arthritis: administer orally 200-600mg once, 3-4 times a day. A maximum of 3200mg can be administered in one day. Mild to moderate pain, common cold: administer orally 200-400mg once, 3-4 times a day. Adjust dosage according to age and symptoms.
Child dose
Juvenile rheumatoid arthritis: administer orally in divided doses of 30-40mg per kg of body weight, 3-4 times a day.

Ingredients

Manufacturer
알파제약(주)

Efficacy & effects

Improvement of symptoms related to arthritis such as rheumatoid arthritis and osteoarthritis

  • Rheumatoid arthritis
  • juvenile rheumatoid arthritis
  • osteoarthritis
  • fever due to the common cold
  • pain
  • back pain
  • dysmenorrhea
  • post-surgical pain
  • ankylosing spondylitis
  • headaches
  • toothaches
  • muscle pain
View approved original text

This medication is effective for joint diseases such as rheumatoid arthritis, juvenile rheumatoid arthritis, and osteoarthritis. It is also used to alleviate fever and pain caused by the common cold, back pain, dysmenorrhea, and post-surgical pain. Additionally, it aids in conditions such as ankylosing spondylitis, headaches, toothaches, muscle pain, neuralgia, acute gout, psoriatic arthritis, soft tissue injuries like sprains and strains, and various non-joint rheumatic diseases. This medication effectively improves symptoms of various pain and inflammatory disorders.

How to take

Adult dose

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, soft tissue injuries, non-joint rheumatic diseases, acute gout, psoriatic arthritis: administer orally 200-600mg once, 3-4 times a day. A maximum of 3200mg can be administered in one day. Mild to moderate pain, common cold: administer orally 200-400mg once, 3-4 times a day. Adjust dosage according to age and symptoms.

Child dose

Juvenile rheumatoid arthritis: administer orally in divided doses of 30-40mg per kg of body weight, 3-4 times a day.

Precautions

This medication can cause gastrointestinal bleeding in individuals who consume a large amount of alcohol daily, so it is essential to consult with a doctor or pharmacist. Those with cardiovascular diseases or risk factors should be cautious, as there may be an increased risk of myocardial infarction or stroke while taking this medication. Long-term or high-dose use of this medication may lead to an increased occurrence of cardiovascular adverse reactions, so symptoms should be closely monitored during treatment. Individuals with ulcers or bleeding in the gastrointestinal tract should not take this medication, as serious problems such as gastrointestinal bleeding or perforation may occur. Patients with severe impairment of heart, liver, or kidney function, or those with blood abnormalities should avoid this medication due to potential health risks. Those allergic to any component of this medication, asthmatics, or individuals who have had hypersensitivity reactions to aspirin or other non-steroidal anti-inflammatory drugs should not use this medication. Avoid taking this medication during the last three months of pregnancy, as it may harm the fetus, and consult a doctor if you are breastfeeding, as the drug may pass into breast milk and affect the infant. Do not exceed the recommended dose, and taking it with other non-steroidal anti-inflammatory drugs may pose risks. During use, blood pressure, liver function, kidney function, etc., should be regularly monitored, and any abnormal symptoms should be immediately discussed with a physician. If symptoms such as severe allergic reactions, skin rashes, difficulty breathing, severe abdominal pain, or blood in stools occur, discontinue use immediately and consult a healthcare professional. This medication should be taken for as short a duration as possible and at the lowest effective dose, and if pain or fever symptoms persist for a long time, it is crucial to consult an expert. It is important to inform and consult with a doctor or pharmacist about any other medications or health conditions currently being taken before using this medication. Store out of reach of children in a safe place, and keep it sealed in its original container to help maintain the safety and effectiveness of the medication.

Side effects and when to seek care immediately

Serious side effects

  • Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction
  • Severe rash, blistering, skin peeling, mucosal pain in the mouth/eyes with high fever → severe skin adverse reaction
  • Asthma attack, cough with fever and breathing difficulties → respiratory problems
  • Yellowing of the skin or eyes (jaundice), extreme lethargy → liver issues (jaundice)
  • Sudden and severe headache, thunderclap headache

Mild side effects

  • Nausea
  • vomiting
  • abdominal pain
  • indigestion
  • diarrhea
  • headache
  • dizziness
  • drowsiness
  • depression
  • lightheadedness
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  • rash
  • skin redness
  • itching
  • low blood pressure
  • high blood pressure
  • palpitations
  • lethargy
  • fever
  • epistaxis (nosebleed)
  • edema (swelling)
  • peripheral edema

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

Do not take this medication in conjunction with other non-steroidal anti-inflammatory drugs, low-dose aspirin, or high-dose methotrexate. Additionally, it is necessary to consult a doctor or pharmacist when taking it alongside ACE inhibitors, lithium, furosemide and thiazide diuretics, coumarin anticoagulants (such as warfarin), or selective serotonin reuptake inhibitors.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. This will help maintain its effectiveness for a longer period.

Appearance and packaging

Appearance

White elliptical tablet

Package unit

30 tablets - 30 tablets/PTP, 10 tablets - 10 tablets/PTP, 10 tablets - 10 tablets/strip

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.