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Prescription medication

Withers Piroxicam Injection

Relief of inflammation and pain in rheumatoid arthritis (osteoarthritis, ankylosing spondylitis) and chronic low back pain.

Widus Pharmaceutical Co., Ltd.

Key information summary

Efficacy & effects
Relief of inflammation and pain in rheumatoid arthritis (osteoarthritis, ankylosing spondylitis) and chronic low back pain.
Adult dosage
Orally: administer 20 mg of piroxicam once daily. Injection: administer 20 mg of piroxicam intramuscularly once daily. The maximum recommended dose per day is 20 mg of piroxicam, and it should be used at the minimum effective dose for the shortest duration possible to reduce the risk of adverse reactions. The therapeutic effect and tolerability should be assessed within 14 days after the administration of this medication, and if continuous treatment is necessary, it should be conducted more frequently.
Ingredients
Piroxicam
Rx / OTC
Prescription medication
Appearance
An injection solution with a light yellow liquid in a brown ampule.

Efficacy & effects

This medication is used only when the effect of other non-steroidal anti-inflammatory drugs is insufficient or there is no response. It is primarily used for chronic inflammatory diseases such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It is also indicated for the treatment of chronic pain conditions such as chronic low back pain, shoulder periarthritis, and adhesive capsulitis. This medication helps to improve inflammation and pain associated with these conditions.

Dosage

Orally: administer 20 mg of piroxicam once daily. Injection: administer 20 mg of piroxicam intramuscularly once daily. The maximum recommended dose per day is 20 mg of piroxicam, and it should be used at the minimum effective dose for the shortest duration possible to reduce the risk of adverse reactions. The therapeutic effect and tolerability should be assessed within 14 days after the administration of this medication, and if continuous treatment is necessary, it should be conducted more frequently.

Precautions

If you consume more than three glasses of alcohol regularly while taking this medication, there may be a risk of gastric bleeding; therefore, you must consult a doctor or pharmacist. This medication can affect the cardiovascular system and may increase the risk of serious cardiovascular diseases such as myocardial infarction or stroke, so those with cardiovascular disease or risk factors should be especially cautious. This medication can cause serious gastrointestinal adverse reactions such as bleeding, ulcers, or perforations, so especially the elderly or those with a history of gastrointestinal diseases should monitor symptoms carefully while taking it. Serious skin reactions may occur, so if symptoms such as rash or erythema arise during the initial treatment, it should be discontinued immediately and medical advice sought. When using this medication, care must be taken to avoid glass particle contamination, and special caution is needed when used for children or the elderly. Patients with a history of gastrointestinal ulcers, bleeding, or perforation, severe liver or kidney impairment, severe cardiac failure, hypertension, pregnant women, breastfeeding mothers, children, and elderly patients over 80 should not take this medication. Careful use is required for patients with a history of peptic ulcers or blood disorders, liver or kidney impairment, cardiac failure, hypertension, or asthma, and caution is needed when used in combination with other drugs. During treatment, various side effects such as indigestion, nausea, vomiting, diarrhea, skin rash, blood disorders, liver dysfunction, or kidney impairment may occur, so you should inform your healthcare provider immediately if symptoms arise. This medication should be avoided in combination with other non-steroidal anti-inflammatory drugs, and potential interactions may occur when combined with specific medications, so be sure to inform your healthcare provider of any medications you are taking. Pregnant or breastfeeding women should not take this medication, especially in late pregnancy, as it may harm the fetus. The safety and efficacy of this medication in children have not been established, so it should not be used in children, and it is also recommended that elderly patients over 80 do not take it. In case of overdose, symptoms may include drowsiness, nausea, vomiting, gastrointestinal bleeding, renal failure, and coma, necessitating immediate medical attention.

Side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), pronounced lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.

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