DaeHan 5% Dextrose with Potassium Sodium Injection No. 2

Adult administration

Typically, for adults, 500–1,000mL is administered by dripping intravenous injection. The infusion rate should not exceed 0.5g of dextrose per kg of body weight per hour. The dosage and infusion rate should be adjusted appropriately based on age, weight, and symptoms.

This medication is a solution containing dextrose, potassium, and sodium, primarily administered by intravenous injection. It contains dextrose, which may increase the depletion of vitamin B1 (thiamine) in the body; hence, patients at risk of vitamin B1 deficiency should use caution. This medication can cause allergic reactions, and in severe cases, life-threatening symptoms such as anaphylaxis may occur; if symptoms develop, administration should be stopped immediately. Due to the potassium component, there is a risk of hyperkalemia, so patients with poor kidney function or heart disease should be particularly cautious. Dextrose can raise blood sugar levels, so patients with diabetes or those who have difficulty controlling blood sugar should regularly check and manage their blood sugar levels. The sodium and chloride components can lead to elevated blood levels of sodium and chloride, resulting in fluid overload, edema, or metabolic acidosis, so patients with related conditions should take care. Additionally, there is a risk of hyponatremia, so particularly children, elderly patients, and those post-surgery should regularly monitor blood sodium levels. The dosage and infusion rate of this medication can lead to fluid overload and electrolyte imbalances, so adjustments and monitoring according to the patient's condition are necessary. In patients with severe malnutrition, refeeding syndrome may occur upon resuming nutrition, so care should be taken while gradually increasing nutrition and observing closely. Patients with hyperkalemia, hypernatremia, hyperglycemia, or excess fluid status should preferably not use this medication. In patients with compromised kidney function, heart failure, obstructive uropathy, etc., caution should be exercised during administration, and frequent blood tests and monitoring of clinical condition are warranted during treatment. In the event of overdose, serious electrolyte imbalances, edema, or cerebral edema may occur, so administration should be stopped immediately and appropriate treatment received. Pregnant or breastfeeding women, newborns, children, and the elderly should be given special attention, and the benefits and risks of this medication should be carefully considered before administration. This medication may interact with other drugs, so if there are other medications being taken, it’s important to inform the healthcare provider and regularly check blood sugar and electrolyte levels. Finally, this medication should be stored at room temperature, and care should be taken to avoid air embolism during administration.

Serious side effects

• Anaphylaxis
• cerebral edema
• pulmonary edema
• peripheral edema
• cardiac arrest
• headache
• seizures

Mild side effects

• Rash
• itching
• hyperkalemia
• hyperglycemia
• hyperosmolar hyperglycemia
• hyponatremia
• fluid overload
• refeeding syndrome
• hypernatremia
• hyperchloremia

This medication should be stored in a sealed container to prevent air or moisture from entering, and it is best to store it at a temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication and prevents degradation.

Appearance

It is a colorless and transparent liquid filled in a colorless and transparent glass container or a plastic infusion container.

Package unit

500mL/bag, 1000mL/bag