Daehan Physiological Saline Injection Solution (Sodium Chloride)

Adult administration

Sodium Chloride is typically administered subcutaneously, intravenously, via drip infusion, or rectally in doses ranging from 20 to 1,000 mL. The dosage and speed of administration should be appropriately adjusted based on age, weight, and symptoms.

This medication should be handled very carefully when opening the ampoule, as glass fragments may contaminate the solution when using glass ampoules. Extra caution is needed when administering to children and the elderly. This medication should not be used in patients with excessively high sodium concentration, excessive fluid retention, or edema and ascites due to liver cirrhosis. Patients with heart or circulatory function problems, weakened kidney function, low blood protein levels, and abnormal sodium or potassium levels should use this medication cautiously. Special attention is needed for pregnant or breastfeeding women, children, and elderly patients. Rapid or excessive administration of this medication can lead to serious side effects such as heart failure, edema, acidosis, and electrolyte imbalances. Local infections, pain, phlebitis, or thrombosis can occur at the injection site, so injection techniques should be performed with care. If side effects occur, administration should be stopped immediately, and the patient's condition should be evaluated with necessary interventions. During the treatment period, regular checks of the patient's fluid balance and electrolyte and acid-base status must be conducted to monitor for any changes. The container for this medication is made from PVC containing a plasticizer called DEHP, which may impact reproductive development in animal studies; however, only trace amounts leach out, making the actual risk very low. Therefore, the importance of using this medication far outweighs concerns regarding DEHP exposure. The elderly may have decreased physiological function, so infusion rates should be slow, and dosages should be adjusted accordingly. When preparing this medication, confirm its suitability as a solvent or diluent, and check for any color changes, precipitates, or crystals before administration. The patient's skin and equipment should be thoroughly disinfected before administration, and the solution should be warmed to body temperature during cold seasons before use. Unused portions after opening or mixing with other medications should not be reused, and administration should be slow to minimize side effects.

Serious side effects

• Congestive heart failure
• edema
• acidosis
• serum electrolyte abnormalities.

Mild side effects

Fever, infection at the injection site, local pain or reactions, venous irritation, thrombophlebitis or phlebitis extending from the injection site, extravasation, and excessive blood volume may occur.

This medication should be stored in a sealed container to prevent exposure to air, ideally at a temperature between 1 and 30 degrees Celsius at room temperature. Proper storage will help maintain the medication's effectiveness.

Appearance

Colorless, clear liquid with a slightly salty taste filled in a colorless transparent ampoule or a plastic (polypropylene or polyethylene) aqueous injection container.

Package unit

20mL X 50 ampoules, 30mL X 40 ampoules