Medication info
Tamofrex Tablets 10 mg (Tamoxifen Citrate)

Tamofrex Tablets 10 mg (Tamoxifen Citrate)

Prescription medicationTabletOral
Ingredient · strength
Tamoxifen Citrate›15.17mg / 1 tablet
Manufacturer / importer
TEVA-HANDOK PHARMA CO., LTD.
Appearance
White tablet
Packaging
30 tablets/box [10 tablets/PTP x 3]
Approval status
Active

MFDS item code 199203344 · Notified 1992.11.13 · Insurance code 626900280

Summary

Main use
Treatment of breast cancer
Who takes it
Adults
Adult dose
Administer tamoxifen orally to adults at 20~40 mg daily in 2 divided doses (morning and evening). Adjust the dose as appropriate according to symptoms.

Ingredients

Importer
TEVA-HANDOK PHARMA CO., LTD.

Efficacy & effects

Treatment of breast cancer

  • Breast cancer
View approved original text

This medication is used in the treatment of breast cancer.

How to take

Adult dose

Administer tamoxifen orally to adults at 20~40 mg daily in 2 divided doses (morning and evening). Adjust the dose as appropriate according to symptoms.

Precautions

This drug should not be used by women who are pregnant or may become pregnant. Patients who are allergic to this drug or have hypersensitivity to its components should not take it. Additionally, it may be prohibited to use if taken with certain other medications, so it is essential to consult with a doctor. Patients with lactose intolerance or specific genetic digestive disorders should not take this drug. Care should be taken when administering to patients with decreased blood cell counts, and any unusual reactions should be immediately reported to medical personnel. This drug can cause various side effects such as nausea, vaginal bleeding, skin rash, and fatigue, so careful monitoring is required. In the case of severe side effects, it may be necessary to reduce or discontinue the medication. Particularly, serious adverse reactions like thrombosis, liver dysfunction, and vision disturbances have been reported, necessitating regular check-ups. Pregnancy should be avoided during treatment with this drug, and women of reproductive age should use effective contraception. It is safest not to use this drug during pregnancy or breastfeeding. Additionally, as this drug can interact with other medications, it is crucial to inform your healthcare provider of all medicines being taken. Caution is needed as fatigue may occur while driving or operating machinery. In the case of overdose, consult with healthcare professionals immediately and receive appropriate treatment. The safety and efficacy in children have not been established, so it is not recommended. This drug should be stored out of reach of children and should not be transferred to other containers.

Side effects

  • Nausea
  • fluid retention
  • vaginal bleeding
  • vaginal discharge
  • skin rash
  • flushing
  • fatigue
  • anemia
  • cataract
  • retinopathy
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  • hypersensitivity reaction
  • increased triglycerides
  • leg cramps
  • myalgia
  • uterine fibroids
  • ischemic vascular disease
  • headache
  • dizziness
  • sensory disturbances
  • vulvar itching
  • endometrial changes
  • hair loss
  • vomiting
  • diarrhea
  • constipation
  • changes in liver enzyme levels
  • fatty liver
  • thromboembolic reaction
  • thrombocytopenia
  • leukopenia
  • vision impairment
  • pancreatitis
  • hypercalcemia
  • endometrial cancer
  • interstitial pneumonia
  • liver cirrhosis
  • neutropenia
  • agranulocytosis
  • corneal changes
  • optic neuropathy
  • uterine sarcoma
  • tumor flare
  • optic neuritis
  • hepatitis
  • cholestasis
  • liver failure
  • hepatocellular damage
  • liver necrosis
  • vascular edema
  • Stevens-Johnson syndrome
  • cutaneous vasculitis
  • bullous pemphigoid
  • erythema multiforme
  • endometriosis
  • cystic ovarian swelling
  • vaginal polyps
  • cutaneous lupus erythematosus
  • porphyria cutanea tarda
  • radiation recall
  • insomnia
  • depressive state
  • appetite loss
  • abdominal pain
  • deep vein thrombosis
  • cerebral thrombosis
  • lower extremity thrombophlebitis
  • phlebitis
  • amenorrhea
  • menstrual irregularities
  • uterine myoma
  • ovarian cyst
  • ovarian follicle
  • sweating
  • retinal atrophy
  • optic atrophy
  • visual impairment
  • blurred vision
  • weight gain
  • edema
  • bone pain
  • lethargy
  • frequent urination

Not everyone experiences these, and they can vary from person to person.

Storage

This drug is sensitive to light and should be stored in a dark container that protects it from light. It is also important to store it at room temperature, avoiding extremes of heat or cold, to maintain its effectiveness.

Appearance and packaging

Appearance

White tablet

Package unit

30 tablets/box [10 tablets/PTP x 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.