Myungmoon Artroda Capsule 25 milligrams (Diacerein)

Adult dose

Adults: Administer 50∼100mg of diacerein orally once or twice daily after meals. Adjust the dose appropriately according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used in patients with inflammatory bowel disease. For example, it should not be administered to patients with ulcerative colitis or Crohn's disease. Additionally, it should not be used in patients with intestinal obstruction syndrome or unexplained abdominal pain. Patients with allergies to this medication or its components, or Rhein-type medications should not be given this medication. This medication should not be administered to patients with liver disease or a history of liver disease, and also not to children under 15 years of age. This medication contains lactose; hence, it should not be administered to patients with genetic disorders that impede lactose breakdown. Patients with a history of small intestine or colon diseases should use this medication cautiously. Pregnant or breastfeeding women also need to be cautious when using this medication. Elderly patients over 65 years of age should use a reduced dose of this medication. The use of this medication may result in gastrointestinal symptoms such as diarrhea, loose stools, and abdominal pain, and long-term use may lead to serious issues such as gastrointestinal bleeding, ulcers, or perforation. Rarely, pigmentation of the rectal mucosa may occur. Severe diarrhea can lead to dehydration or electrolyte imbalance, so if diarrhea occurs, medical consultation should be sought immediately. Skin reactions such as itching, rash, and eczema may occur, and it may affect liver function, resulting in elevated liver enzyme levels. Adhere strictly to your doctor's instructions when taking this medication for long periods. If diarrhea occurs, discontinue the medication and follow your doctor's instructions, avoiding the use of laxatives concurrently. Signs of liver damage may emerge, so regular liver function tests should be conducted, and co-administration with other medications or alcohol that could stress the liver should be avoided. Taking antacids containing calcium, magnesium, or aluminum, or salt concurrently may impede the absorption of this medication, so these should be spaced at least 2 hours apart. Concurrent use with diuretics may lead to increased diuretic effect and cause risks of dehydration or hypokalemia, so be cautious. The combination with heart medications, particularly cardiac glycosides, may increase the risk of arrhythmias and should be approached with caution. Pregnant women are advised to avoid use due to the possible risk of delayed bone formation in the fetus, and breastfeeding women should also avoid administration as the drug can pass into breast milk.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rash, eczema, increased serum liver enzymes

This medication should be stored in a tightly closed container to prevent air or moisture entry, at a temperature between 1 and 30 degrees Celsius. This ensures that the medication retains its effectiveness and can be used safely.

Appearance

This medication is a hard capsule with an upper orange and lower white color, containing a brownish-yellow substance.

Package unit

500 capsules/bottle, 100 capsules/bottle, 30 capsules/bottle