Ranis Tablet (Ranitidine Hydrochloride)

Adult dose

For adults, take 150 mg of ranitidine orally, twice daily, in the morning and before bedtime. For treatment of gastric and duodenal ulcers, take 150 mg orally twice daily or 300 mg once daily at bedtime. Specifically for patients with duodenal ulcers, taking 300 mg twice daily can yield a higher treatment rate. As maintenance therapy for recurrent ulcer patients, take 150 mg orally once daily at bedtime.

Child dose

For children aged 8 to 18 years, 150 mg (2 mg per kg of body weight) may be given once, twice a day.

This drug should not be used in patients with hypersensitivity to any of its components. It should not be administered to patients with a history of acute porphyria as it may trigger an acute attack. As it contains lactose, it should not be used in patients with lactose intolerance or specific genetic metabolic disorders. In patients with impaired renal function, this medication can stay in the body longer, so the dose should be reduced or the dosing interval should be extended. It should also be used cautiously in patients with impaired liver function. Past drug allergy sufferers should use this medication carefully. Elderly patients are at higher risk of side effects, so caution is required. Patients taking NSAIDs need regular health checks, especially. Gastric cancer symptoms can be masked, so patients over middle age with gastric ulcers or newly developed or changed dyspeptic symptoms should be screened for malignancy before treatment. Patients with Helicobacter pylori infection and gastric or duodenal ulcers should undergo eradication therapy simultaneously. Rarely, this medication can cause serious allergic reactions, blood abnormalities, liver dysfunction, cardiac rhythm disturbances, gastrointestinal issues, neurological problems, and skin rashes. If any unusual symptoms occur, stop using it immediately and consult a doctor. During treatment, closely observe the disease course, and if ineffective, switch to other treatment methods. There may be an increased risk of pneumonia in the elderly or patients with chronic diseases, so caution is warranted. If dizziness or drowsiness develops after taking this medication, avoid driving or operating hazardous machinery. There may be interactions with other drugs, so you must inform your healthcare provider about any concurrent medications. Especially with anticoagulants or certain heart medications, blood coagulation status should be closely monitored. Women who are pregnant or may become pregnant or are breastfeeding should only use this drug cautiously when necessary. Safety in children has not been adequately established, so caution is needed when using. Elderly patients may experience increased drug concentration due to decreased kidney function, requiring dosage adjustments. No specific severe problems have been reported with overdose, but appropriate treatment such as vomiting or gastric lavage may be required. Keep this medication out of reach of children and avoid transferring it to other containers.

Serious side effects

• Urticaria
• angioedema
• anaphylactic shock
• skin rash
• erythema multiforme
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• aplastic anemia
• atrioventricular block
• severe edema

Mild side effects

Granulocytopenia, elevated serum creatinine levels, leukopenia, thrombocytopenia, bone marrow suppression, aplastic anemia, hypogranulocytosis, pancytopenia, acquired immune hemolytic anemia, eosinophilia, hepatic dysfunction (elevated AST, ALT, γ-GTP, ALP levels), hepatitis, bradycardia, atrioventricular block, tachycardia, vasculitis, constipation, nausea, vomiting, abdominal distension, abdominal pain, anorexia, diarrhea, acute pancreatitis, dizziness

Store this medication in a container protected from light and air, preferably at a temperature between 1 and 30 degrees Celsius. This way, the effectiveness of the drug is well preserved and its degradation can be prevented.

Appearance

Off-white to yellowish round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle