Kolon Brexine 10 mg (Piroxicam Beta-Cyclodextrin)

Adult dosage

(Oral) Adults: Administer 20 mg of piroxicam orally once daily. The maximum recommended daily dose is 20 mg of piroxicam. To reduce the risk of adverse reactions, use the lowest effective dose for the shortest possible duration. Therapeutic effect and tolerability should be reviewed within 14 days after starting this medicine. If continued treatment is considered necessary, more frequent reviews should be conducted. (Injection) Adults: Inject 20 mg of piroxicam intramuscularly once daily. The maximum recommended daily dose is 20 mg of piroxicam. To reduce the risk of adverse reactions, use the lowest effective dose for the shortest possible duration. Therapeutic effect and tolerability should be reviewed within 14 days after starting this medicine. If continued treatment is considered necessary, more frequent reviews should be conducted. The oral or suppository formulation of this medicine may be administered concomitantly; however, the total dose administered by both routes must not exceed the maximum recommended daily dose.

This medication may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic beverages a day, hence it is essential to consult a doctor or pharmacist. This medication may affect the cardiovascular system, increasing the risk of serious cardiovascular diseases such as myocardial infarction or stroke. Patients with a history of cardiovascular disease or risk factors should exercise more caution. This medication can lead to serious problems such as gastrointestinal bleeding, ulcers, and perforation; therefore, those with a history of gastrointestinal diseases or the elderly should carefully consider its use before taking. It can cause severe skin reactions, so if rashes or skin symptoms occur, the medication should be discontinued immediately, and a doctor should be consulted. This medication is not to be given to patients with a history of gastrointestinal ulcers, bleeding, perforation, severe liver, kidney, or heart diseases, or a history of drug allergies. It is particularly prohibited for pregnant or breastfeeding women, individuals over the age of 80, and children. Regular tests such as liver, kidney, and blood tests are necessary during prolonged use, and if any abnormal symptoms arise, medical advice should be sought immediately. Due to multiple drug interactions, it is vital to inform healthcare professionals of any other medications currently being taken, especially when used in conjunction with anticoagulants, diuretics, lithium, methotrexate, etc. In case of overdose, symptoms may include drowsiness, nausea, vomiting, and gastrointestinal bleeding; thus, it is crucial to adhere strictly to dosage instructions and visit a healthcare facility if abnormal symptoms occur. This medication should be stored out of the reach of children and it is advisable not to transfer it to another container.

Peptic ulcer, hematemesis, hematochezia, gastric bleeding, epigastric pain, gastric discomfort, loss of appetite, nausea, vomiting, diarrhea, loose stool, stomatitis, dyspepsia, abdominal bloating, constipation, glossitis, shock, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), Stevens-Johnson syndrome, Lyell syndrome, phototoxic reaction, nail dystrophy, abnormal nail growth, hair loss, vesicular reactions, anemia, granulocytopenia, thrombocytopenia, aplastic anemia, bone marrow suppression, purpura, leukopenia, pancytopenia, eosinophilia, hypertension, congestive heart failure, acute cardiac disease, jaundice, hepatitis, elevated AST/ALT, elevated ALP, elevated LDH, acute renal failure, fluid retention, oliguria, hematuria, proteinuria, elevated BUN, elevated serum creatinine, hyperkalemia, rash, pruritus, bronchospasm, urticaria, angioedema, vasculitis, serum sickness, drowsiness, dizziness, headache, tinnitus, paresthesia of hands and feet, depression, irritability, hallucinations, mood changes, mental confusion, allergic edema of the face and hands, thirst, general malaise, blurred vision, eye irritation, shoulder stiffness, fever, palpitations, respiratory distress

This medication may be sensitive to air or humidity, so it must be stored in a tightly closed container. Furthermore, it is best to store it at room temperature, away from excessively hot or cold environments.

Appearance

Hexagonal tablets that are yellow to lemon yellow.

Package unit

30 tablets/bottle, 100 tablets/bottle, 500 tablets/bottle