Rosid 150 mg (Ranitidine Hydrochloride)

Adult dose

For adults, a single dose of 150 mg is taken orally twice a day, in the morning and at bedtime. 1) Gastric and duodenal ulcers: A single dose of 150 mg can be taken orally twice a day, or a single dose of 300 mg can be taken once daily at bedtime. Particularly for duodenal ulcer patients, taking 300 mg twice a day, in the morning and at bedtime, yields higher treatment rates. Maintenance therapy involves a dose of 150 mg once a day at bedtime. 2) Gastroesophageal reflux disease.

Child dose

For children aged 8 to 18 years, a single dose of 150 mg (2 mg per kg of body weight) may be administered twice a day.

This medication should not be used in patients who have had allergic reactions to any of its ingredients. It should also be avoided in patients with a history of acute porphyria as it may worsen symptoms. For patients with decreased kidney function, the concentration of this medication may increase, so dosages should be reduced or intervals between doses extended. Caution is also warranted for patients with impaired liver function. Patients with a history of drug allergies should be administered with care. Elderly patients should be cautious due to an increased risk of side effects from decreased body function. Patients taking non-steroidal anti-inflammatory drugs, particularly elderly patients or those with a history of peptic ulcers, will require regular monitoring. As this medication can mask symptoms of gastric cancer, patients with gastric ulcers or new dyspeptic symptoms in middle age or older should undergo evaluation for malignancy prior to use. Patients with Helicobacter pylori-infected gastric and duodenal ulcers require eradication therapy. Rarely, serious allergic reactions such as anaphylactic shock may occur; if any unusual symptoms arise during treatment, it should be discontinued immediately and appropriate treatment provided. Treatment should be stopped if symptoms of hypersensitivity such as rash, hives, fever, or difficulty breathing develop. If blood disorders emerge, such as fatigue, bleeding, or fever, a blood test should be conducted and necessary measures taken. If hepatic dysfunction symptoms arise, medication should be stopped immediately, and a physician should be consulted. There have been reports of rare occurrences of arrhythmias or vasculitis, so caution is advised if symptoms occur. Gastrointestinal symptoms such as constipation, nausea, or abdominal pain may develop; if discomfort persists, medical attention should be sought. If neurological symptoms such as dizziness, drowsiness, or headache occur, driving or operating hazardous machinery should be avoided. Muscle pain or joint pain, and rarely severe muscle damage, may occur, necessitating discontinuation of the medication if these symptoms arise. Skin rash or hair loss may occur. This medication may interact with other drugs, so it is essential to inform healthcare providers of any concurrently taken medications. Women who are pregnant or may become pregnant should use this medication cautiously, and nursing mothers should consult a physician before use. Safety in children has not been sufficiently established, so caution is advised. Elderly patients may experience increased drug concentration due to decreased kidney function; thus, dosage adjustments may be necessary. This medication may give false positive results in some tests; a discussion with healthcare providers about testing methods is warranted. In case of overdose, appropriate treatments such as vomiting or gastric lavage may be needed, and in severe cases, hemodialysis may be necessary. Store the medication out of reach of children, and do not transfer it to another container for safety. This medication reduces gastric acid secretion, which may promote bacterial growth in the stomach; therefore, long-term use may necessitate ophthalmological examinations.

Serious side effects

Shock (anaphylactic shock), hives, angioedema (severe swelling), chest pain (tightness in the chest), bronchospasm, hypotension, edema, jaundice, hepatitis (liver dysfunction), altered consciousness, convulsions (tonic), myoclonus, acute pancreatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), aplastic anemia, atrioventricular block (heart block)

Mild side effects

Hives, angioedema, rash, fever, bronchospasm, hypotension, chest pain, granulocytopenia, increased serum creatinine levels, leukopenia, thrombocytopenia, aplastic anemia, agranulocytosis, pancytopenia, acquired immune hemolytic anemia, eosinophilia, liver dysfunction (increased AST, ALT, γ-GTP, ALP levels), bradycardia, atrioventricular block, tachycardia, vasculitis, constipation, nausea, vomiting

This medication should be stored in a tightly sealed container at dry room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medication over time.

Appearance

White round film-coated tablet

Package unit

100 tablets (10 tablets/Alu-Alu X 10)