Medication info
Hutex Famotidine Tablets 10 Milligrams

Hutex Famotidine Tablets 10 Milligrams

Prescription medicationTablet
Ingredient · strength
Famotidine›10mg / 1 tablet
Manufacturer / importer
한국휴텍스제약(주)
Appearance
Pale green, round, film-coated tablet
Packaging
500 tablets/bottle
Approval status
Active

MFDS item code 199200163 · Notified 1992.08.07 · Insurance code 649101380

Summary

Main use
Improvement of gastric ulcers and upper gastrointestinal bleeding
Who uses it
Adults
Adult dosage
For oral administration, take 20 mg twice a day (after breakfast, after dinner, or at bedtime) or 40 mg once daily (at bedtime). Alternatively, take 10 mg twice a day or 20 mg once daily orally. For injectable administration, dissolve 20 mg in 20 mL of normal saline or dextrose injection and slowly administer by intravenous injection twice a day (every 12 hours) or mix with an infusion.

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Improvement of gastric ulcers and upper gastrointestinal bleeding

  • Gastric ulcer
  • duodenal ulcer
  • anastomotic ulcer
  • upper gastrointestinal bleeding
  • acute stress ulcer
  • hemorrhagic gastritis
  • gastroesophageal reflux disease
  • Zollinger-Ellison syndrome
  • gastric mucosal erosion
  • gastric mucosal bleeding
  • gastric mucosal redness
  • gastric mucosal edema
View approved original text

This medication can be administered orally and by injection and is primarily used for the treatment of gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding (such as peptic ulcers, acute stress ulcers, hemorrhagic gastritis, etc.), gastroesophageal reflux disease, Zollinger-Ellison syndrome, and other related conditions. It is also effective in improving gastric mucosal lesions that appear during acute exacerbations of both acute and chronic gastritis. In injectable form, it can be used for pre-anesthetic administration, contributing to patient safety. Taking this medication helps reduce damage to the gastric mucosa, prevent bleeding, and improve gastrointestinal disorder symptoms. Therefore, this medication is widely used for treating gastrointestinal-related conditions.

Dosage and Administration

Adult dosage

For oral administration, take 20 mg twice a day (after breakfast, after dinner, or at bedtime) or 40 mg once daily (at bedtime). Alternatively, take 10 mg twice a day or 20 mg once daily orally. For injectable administration, dissolve 20 mg in 20 mL of normal saline or dextrose injection and slowly administer by intravenous injection twice a day (every 12 hours) or mix with an infusion.

Precautions

This medication should not be used in individuals who are hypersensitive to its components or allergic to other H2 receptor antagonists. It also contains lactose, so individuals with lactose intolerance, lactose enzyme deficiency, or genetic disorders like glucose-galactose malabsorption should avoid this medication. Patients with a history of allergic reactions to medications or impaired kidney function should use this medication with caution. Dosage may need to be reduced or dosing intervals increased due to the risk of increased blood concentration because of weak kidney function. Patients with heart disease should be cautious due to the risk of cardiovascular side effects. Individuals with poor liver function need to be careful as symptoms may worsen, and elderly patients should also be closely monitored. This medication may rarely cause severe allergic reactions, blood abnormalities, skin diseases, liver dysfunction, muscle damage, heart rhythm disorders, consciousness disturbances, nephritis, pneumonia, etc. If such symptoms occur, stop the medication immediately and consult a healthcare professional. During treatment, symptoms and blood, liver, and kidney functions should be regularly monitored, and if there is no efficacy, alternative treatment methods can be considered. This medication should be swallowed with saliva or water as it dissolves in the mouth but is not absorbed through the oral mucosa. If a patient undergoing dialysis uses this medication in conjunction with phosphate binders, the effectiveness of calcium carbonate may be diminished. There may be interactions with other drugs, especially antifungals or certain chemotherapy agents, so caution is required when using these medications together. Elderly patients may experience increased blood concentration due to decreased kidney function, necessitating dosage adjustments. Women who are pregnant or may become pregnant should use this medication only if the benefits outweigh the risks, and breastfeeding women should discontinue nursing as the medication can be passed through breast milk. The safety for children has not been adequately established, so experience in this regard is limited. For oral disintegrating tablet forms, place on the tongue and allow to dissolve with saliva; do not take without water while lying down. This medication may mask symptoms of gastric cancer, so it should only be used after confirming that it is not gastric cancer.

Side effects and when to seek care immediately

Serious side effects

Shock, hypersensitivity (anaphylaxis, breathing difficulties, generalized flushing, angioedema, urticaria), agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia, Stevens-Johnson syndrome, Lyell's syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia, ventricular fibrillation, consciousness disturbances, seizures, interstitial nephritis, acute renal failure, interstitial pneumonia, contractile failure.

Mild side effects

  • Constipation
  • diarrhea
  • soft stool
  • dry mouth
  • nausea
  • vomiting
  • abdominal bloating
  • loss of appetite
  • stomatitis
  • elevated blood pressure
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  • facial flushing
  • tinnitus
  • bradycardia
  • tachycardia
  • atrioventricular block
  • bronchospasm
  • elevated AST(GOT)
  • ALT(GPT)
  • ALP
  • elevated total bilirubin and LDH
  • general fatigue
  • lethargy
  • headache
  • drowsiness
  • insomnia
  • hallucinations
  • anxiety
  • agitation
  • decreased libido
  • sensory abnormalities
  • heaviness in limbs
  • dizziness
  • menstrual irregularities
  • gynecomastia
  • arthralgia
  • CK.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture; therefore, it should be stored in a tightly sealed container to prevent leakage. Avoid storing it in excessively hot or cold places, and it is best to keep it at normal room temperature.

Appearance and packaging

Appearance

Pale green, round, film-coated tablet

Package unit

500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.