Seroxen Tablets (Naproxen Sodium)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: As naproxen sodium, 275-550 mg orally twice a day (every 12 hours). 2. Acute gout: An initial dose of 825 mg orally, followed by 275 mg orally every 8 hours until the attack subsides. 3. Musculoskeletal disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis: An initial dose of 550 mg of naproxen sodium,

Patients who regularly consume three or more alcoholic beverages daily should consult a doctor or pharmacist before taking this medicine, as taking it with alcohol may increase the risk of gastrointestinal bleeding. This drug may affect the cardiovascular system, so those at risk of heart disease or stroke should exercise extra caution. If symptoms related to the heart or cerebrovascular system occur while taking this medication, medical consultation should be sought immediately. Additionally, serious gastrointestinal issues such as bleeding, ulcers, or perforations can develop; therefore, those with a history of gastrointestinal diseases or the elderly should be particularly careful. If gastrointestinal bleeding symptoms occur, immediate treatment should be sought. Individuals with a history of peptic ulcers, severe blood abnormalities, liver dysfunction, kidney dysfunction, heart failure, hypertension, or other serious diseases should not take this medication. Patients with allergies or hypersensitivity reactions to this drug or other non-steroidal anti-inflammatory drugs (NSAIDs) should also avoid taking it. Caution is advised for those with a history of peptic ulcers or blood abnormalities, liver or kidney function decline, asthma, hypertension, and heart dysfunction when using this medication. This drug can rarely cause various side effects, including shortness of breath, skin rashes, gastrointestinal bleeding, liver dysfunction, kidney issues, and neurological symptoms. If any abnormal symptoms occur, discontinue use immediately and consult a healthcare professional. Before taking, it is essential to verify potential drug interactions with this medication, especially when taken with other anti-inflammatory drugs, antihypertensive medications, diuretics, anticoagulants, and anticancer drugs. During pregnancy, particularly in the third trimester, it may pose risks to the fetus, so women who are pregnant or may become pregnant should avoid taking it or consult a doctor. If breastfeeding, this medication may pass into breast milk and affect the baby, so it is advised to refrain from taking it. Children, especially those under the age of 2, should not use it as safety has not been established, and the elderly should be administered the minimum dosage cautiously due to a higher risk of side effects. If taking this medication long-term, regular blood tests and liver function tests should be performed to check for abnormalities, and if any unusual symptoms occur during the course of treatment, immediate consultation with healthcare professionals is necessary. In case of overdose, symptoms like drowsiness, indigestion, and vomiting may appear, so emergency treatment should be sought if these symptoms are present. Lastly, store this medication in a secure place out of the reach of children and do not transfer it to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, peeling skin, pain in mouth/eyes mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory issues accompanied by cough and fever, jaundice (yellowing of skin or eyes), severe lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Itching
• rash
• gastrointestinal discomfort
• stomach pain
• abdominal pain
• nausea
• vomiting
• loss of appetite
• indigestion
• heartburn

Drug interactions

This medication should not be taken with other non-steroidal anti-inflammatory drugs and naproxen derivatives, aspirin, and high-dose methotrexate. It may also interact with hydantoin anticonvulsants, sulfa drugs, sulfonylurea hypoglycemic agents, propranolol and other beta-blockers, ACE inhibitors (such as captopril), loop diuretics and thiazide diuretics, probenecid, lithium, low-dose methotrexate, warfarin and other anticoagulants.

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is recommended to keep it in a cool, dry place away from direct sunlight.

Appearance

White oblong film-coated tablets

Package unit

10 tablets/PTP