Innoen Sodium Chloride - Glucose (1:4) Injection

Adult administration

Typically, adults receive an intravenous infusion of 500-1,000 mL at a rate of 300-500 mL per hour (75-120 drops per minute).

Child administration

For children, the administration rate is 50-100 mL per hour. Especially for newborns and premature infants, rapid infusion (more than 100 mL per hour) should not be performed.

This drug contains glucose, which may increase the consumption of vitamin B1 (thiamine) in the body during intravenous administration. This increases the risk of rapid thiamine deficiency, so caution is necessary. This medication should not be used in patients with excessive fluid in the body, those with storage dehydration, or patients with hypokalemia (low potassium levels in the blood). It should be administered with caution in patients with impaired kidney function, weak heart function, hypertonic dehydration, those with urinary obstruction making urination difficult, diabetic patients, and those with hyperchloremia (high chloride levels in the blood). Rapid administration of this medication can lead to cerebral edema, pulmonary edema, peripheral edema, acidosis, and conditions of excessive hydration. Especially in newborns or premature infants, rapid administration can more easily lead to fluid overload. There is also a risk of thrombosis in the veins at the injection site, so caution is required. Regular monitoring of blood glucose, electrolytes in the blood, and fluid status should be performed during administration to check for abnormalities. During pregnancy, the impact on the fetus has not been fully clarified, so it should only be used when the therapeutic effect outweighs the risks. The use of this medication during labor poses a risk of hyperglycemia and metabolic acidosis for both mother and fetus, so careful judgment is needed. Newborns, especially preterm or low-birth-weight infants, may struggle with blood sugar control, leading to hypoglycemia or hyperglycemia, necessitating close observation. For infants and the elderly, rapid or prolonged administration should be avoided, and in elderly patients with weak heart or kidney function, caution should be taken to reduce circulatory burden. In cases of overdose, diuretics should be used to adjust fluid levels in the body. Prior to administration, skin and injection equipment should be thoroughly sterilized to prevent infection, and in cold weather, the medication should be warmed to body temperature before use. It should be used immediately after opening, and any remaining medication should be discarded; the injection should be administered slowly into the vein. To reduce the risk of air embolism, injection containers should not be connected continuously. This medication should be stored at room temperature and requires proper storage and handling.

Serious side effects

Cerebral edema, pulmonary edema

Mild side effects

• Peripheral edema
• acidosis
• water intoxication
• thrombosis

This medication must be stored in a sealed container to protect it from air, and it is safe to store at a temperature between 1 degree and 30 degrees Celsius. This helps maintain the effectiveness of the medication and prevents degradation.

Appearance

A colorless and transparent injection solution packed in a container made of high-density polyethylene that is semi-transparent on the outside.

Package unit

500,1000 milliliters