Epileptol CR Tablets (Carbamazepine)

Adult dose

1. Epilepsy Start treatment at a low dose and increase it slowly until the optimal effect is achieved. The dose of this medicine should be adjusted to adequately control seizures in each patient. Determining the blood concentration may help achieve the optimal dose. The therapeutic blood concentration of carbamazepine for epilepsy is known to be 4-12 μg/mL (17-50 micromoles/L). Adults: The initial dose is 200-400㎎ of carbamazepine per day, given orally in 1-2 divided doses. Increase the dose slowly until the optimal effect is achieved (600㎎ per day). The dose may be increased to 1200㎎ per day depending on symptoms. 2. Trigeminal neuralgia Adults: The initial dose of this medicine is 200-400㎎ per day, given in divided doses up to 600 mg per day. Depending on symptoms, the dose may be increased to 800mg per day. 3. Mania, manic episodes in bipolar disorder, and agitation in schizophrenia Adults: The initial dose of this medicine is 200-400㎎ per day, given in 1-2 divided doses. Increase the dose slowly until the optimal effect is achieved (600㎎ per day). The dose may be increased to 1200㎎ per day depending on symptoms. Adjust the dose as appropriate according to age and symptoms.

Child dose

Children: Administer 100-600㎎ per day in divided doses according to age and symptoms.

This medication is used in the treatment of epilepsy and may lead to changes in mental health such as suicidal thoughts or actions, and depression, so careful monitoring is necessary. Severe skin reactions may occur, especially in individuals with certain genetic backgrounds among Asians; hence, genetic testing is recommended before starting this medication. During pregnancy, this medication may cause malformations or growth retardation in the fetus; therefore, women who are pregnant or planning to become pregnant should consult a specialist and use effective contraceptive methods while on this medication. Patients with allergies to this medication, any specific heart diseases, or blood disorders should avoid taking it, and due to many potential drug interactions, they must inform healthcare professionals about any concurrent medications. Common side effects include dizziness, drowsiness, and motor coordination disturbances, so caution is necessary when driving or operating hazardous machinery. Regular blood tests and liver function tests should be performed, and if symptoms of hyponatremia or liver function impairment occur, immediate consultation with a healthcare professional is necessary. This medication may affect thyroid function, so patients with thyroid disease should be monitored carefully. In case of overdose, severe problems may arise in the central nervous system, heart, and respiratory system, requiring immediate emergency treatment. This medication should be stored out of the reach of children and not kept outside of its original container for safety. If any unusual symptoms or side effects are suspected during use, immediate consultation with a healthcare professional is required, and discontinuation should not be done arbitrarily.

• Suicidal thoughts
• suicidal behavior
• depression
• abnormal changes in mood and behavior
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• dizziness
• headache
• ataxia
• drowsiness

This medication may be sensitive to air or moisture, so to safely store it, it should be kept in a sealed container. This will help maintain the drug's effectiveness for a long time.

Appearance

Yellow to yellowish oval film-coated tablets

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 500 tablets/bottle, For domestic use - 1000 tablets/box [10 tablets/PTP × 100], For export - 30 tablets/box [10 tablets/PTP × 3], For export - 20 tablets/bottle