Samchundang Gliclazide Tablet (Gliclazide)

Adult dose

Tablets and capsules: Start with 40-80 mg of gliclazide daily, administered orally in 1-2 divided doses. Depending on the patient's blood sugar status, the dose may be increased to a maximum of 320 mg daily in two doses, not exceeding 160 mg in a single dose. Extended release: Administer 30-120 mg of gliclazide in the morning daily, adjusting the dose based on blood sugar levels. The initial dose is 30 mg per day.

This medication is a sulfonylurea that works to lower blood sugar levels. However, caution is required as hypoglycemia may occur when using this medication. Especially, severe hypoglycemia can lead to loss of consciousness, so it is critical to adhere strictly to the dosage and check blood sugar regularly. Symptoms of hypoglycemia may include weakness, headache, tremors, confusion, and visual disturbances; if these symptoms occur, immediate ingestion of sugar is necessary. This medication should not be used by patients with type 1 diabetes, diabetic ketoacidosis, severe liver or kidney impairment, severe infections, or those undergoing surgery, patients with severe gastrointestinal disorders, and individuals allergic to any components of this medication. Additionally, pregnant or nursing women should not take this medication, and elderly patients or those with impaired liver or kidney function should use it cautiously due to a higher risk of hypoglycemia. This medication can interact with other drugs, so it is advised to consult a physician, especially when taken with miconazole, certain anti-inflammatory agents, alcohol, or beta-blockers. During treatment, regular meals, exercise, and self-monitoring of blood sugar are very important, as skipping meals or irregular eating can increase the risk of hypoglycemia. In case of overdose, severe hypoglycemic symptoms may develop, and immediate medical attention is required.

Serious side effects

• Severe allergic reactions: hives, severe swelling (angioedema).
• Severe skin reactions: severe rash, large blistering rash, vesicular reactions (Stevens-Johnson syndrome and toxic epidermal necrolysis), skin peeling.
• Liver problems (jaundice): yellowing of the skin or eyes (jaundice).
• Respiratory issues: shallow breathing.
• Severe neurological symptoms: severe headache, disorientation, seizures, consciousness disturbances.
• Severe swelling or urination issues: significant overall.

Mild side effects

• Symptoms of hypoglycemia: weakness, intense hunger, tremors, headache, sensory disturbances, agitation, reduced concentration, aggression, nausea, vomiting, fatigue, sleep disturbances, decreased cognition and slow reactions, depression, confusion, visual and speech disturbances, aphasia, partial paralysis, dizziness, loss of self-control, delirium, shallow breathing, bradycardia, drowsiness, consciousness disturbances, seizures, etc.
• Signs of adrenergic counter-regulation: sweating, palpitations, cold and clammy skin.

This medication should be stored in a tightly closed container to prevent air exposure, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. This helps maintain the medication's effectiveness for a longer period.

Appearance

White round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle