Medication info
GL Famotidine Tablets 20 Milligrams

GL Famotidine Tablets 20 Milligrams

Prescription medicationTablet경구 · 근육 · 정맥
Ingredient · strength
Famotidine›20mg / 1 tablet
Manufacturer / importer
지엘파마(주)
Appearance
White, round film-coated tablet
Packaging
30 tablets/bottle, 500 tablets/bottle, 1000 tablets/bottle
Approval status
Active

MFDS item code 199002111 · Notified 1990.04.23

Summary

Main use
Improvement of gastric ulcers and upper gastrointestinal bleeding (peptic ulcers, acute stress ulcers, etc.)
Who uses it
Adults
Adult dosage
For oral administration, for gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, and Zollinger-Ellison syndrome: a single dose of 20 mg twice daily (after breakfast, after dinner, or at bedtime) or a single dose of 40 mg once daily (at bedtime). For improvement of gastric mucosal lesions (acute gastritis, acute exacerbation of chronic gastritis): 10 mg twice daily or 20 mg once daily (at bedtime) per dose.

Ingredients

Manufacturer
지엘파마(주)

Efficacy & effects

Improvement of gastric ulcers and upper gastrointestinal bleeding (peptic ulcers, acute stress ulcers, etc.)

  • Gastric ulcer
  • duodenal ulcer
  • anastomotic ulcer
  • upper gastrointestinal bleeding
  • acute stress ulcer
  • hemorrhagic gastritis
  • gastroesophageal reflux disease
  • Zollinger-Ellison syndrome
  • gastric mucosal lesions
  • erosion
  • bleeding
  • redness
View approved original text

This medication is used for the treatment of gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding caused by peptic ulcers or acute stress ulcers. It also helps relieve symptoms of several diseases that cause damage to the gastric mucosa, such as hemorrhagic gastritis, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. It is effective in improving erosion, bleeding, redness, and swelling of the gastric mucosa during acute exacerbations of acute gastritis and chronic gastritis. As an injectable form, it is used to treat upper gastrointestinal bleeding and Zollinger-Ellison syndrome, and is also used preoperatively. This medication is effective in protecting the gastric mucosa and improving symptoms related to various gastrointestinal disorders.

Dosage and Administration

Adult dosage

For oral administration, for gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, and Zollinger-Ellison syndrome: a single dose of 20 mg twice daily (after breakfast, after dinner, or at bedtime) or a single dose of 40 mg once daily (at bedtime). For improvement of gastric mucosal lesions (acute gastritis, acute exacerbation of chronic gastritis): 10 mg twice daily or 20 mg once daily (at bedtime) per dose.

Precautions

This medication should not be used by patients who have had allergic reactions to specific components or similar drugs. It contains lactose, so patients with a deficiency in lactose-degrading enzymes or genetic conditions that prevent lactose digestion should not take this medication. Patients with a history of drug allergies, decreased kidney function, heart diseases, poor liver function, and elderly patients should use this medication with caution. Serious allergic reactions, blood cell reductions, severe damage to the skin and mucous membranes, hepatic dysfunction, muscle damage, cardiac rhythm problems, consciousness disorders, renal inflammation, and lung inflammation could occur, so careful observation is required. If these symptoms appear, immediately discontinue the medication and seek medical treatment. The tablet dissolves in the mouth but is not absorbed in the mouth, so it should be swallowed with a sufficient amount of saliva or water. It is important to regularly undergo blood tests and liver and kidney function tests, while carefully monitoring treatment progress. Patients receiving blood dialysis should be cautious when using this medication with certain phosphate binders, as the efficacy of the binders may decrease. The medication may lose effectiveness when used with some antifungal agents or chemotherapeutics, so consult a doctor or pharmacist. Elderly individuals may have reduced kidney function, which could increase drug concentration, therefore care should be taken to reduce dosage or extend administration intervals. Women who are pregnant or may become pregnant should only use this medication when the benefits outweigh the risks, and safety has not been fully confirmed. Nursing mothers should discontinue breastfeeding as this medication may be passed into breast milk. The safety of this medication has not been sufficiently confirmed for children, so use with caution. In particular, the oral disintegrating tablet form of this medication should be placed on the tongue and dissolved with saliva before ingestion, and should not be taken while lying down without water. Finally, taking this medication may mask symptoms of gastric cancer, so it should only be used when it is certain that it is not gastric cancer.

Side effects and when to seek care immediately

Serious side effects

Shock, hypersensitivity (anaphylaxis, dyspnea, generalized flushing, angioedema including facial swelling and throat swelling, urticaria), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia (generalized fatigue, weakness, subcutaneous or mucosal bleeding, fever), Stevens-Johnson syndrome (mucocutaneous syndrome), Lyell's syndrome (toxic epidermal necrolysis), hepatic dysfunction, jaundice, rhabdomyolysis (hyperkalemia, myoglobinuria, serum muscle enzyme elevation)

Mild side effects

  • Rash
  • urticaria (erythema)
  • facial swelling
  • leukopenia
  • eosinophilia
  • constipation
  • diarrhea or loose stools
  • dry mouth
  • nausea or vomiting
  • abdominal distension
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  • loss of appetite
  • stomatitis
  • elevated blood pressure
  • facial flushing
  • tinnitus
  • bradycardia
  • tachycardia
  • AV block
  • bronchospasm
  • elevated AST (GOT)
  • ALT (GPT)
  • ALP
  • elevated total bilirubin
  • elevated LDH
  • liver function abnormalities
  • hepatitis
  • generalized fatigue
  • lethargy
  • headache
  • drowsiness
  • insomnia
  • hallucinations

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a sealed container to prevent air ingress, and it is best to keep it at room temperature between 1°C and 30°C. Proper storage will maintain the efficacy of the medication and prevent deterioration.

Appearance and packaging

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle, 1000 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.