Gromin Capsule 10mg (Clomipramine Hydrochloride)

Adult dosage

For oral administration, the initial dose is 10mg per day as clomipramine hydrochloride. Gradually increase the dose to 30-150mg per day, administering in divided doses or taking once at bedtime. The maintenance dose is 30-50mg per day. For injection, the initial dose is 25-50mg per day as clomipramine hydrochloride by intramuscular injection. Increase the dose daily by 25mg to a total of 100-150mg per day.

This medication may increase the risk of suicidal thoughts or behaviors in children, adolescents, and young adults with major depression or psychiatric disorders, so a physician should carefully consider whether to prescribe it. This medication can be dangerous when taken with certain drugs, especially MAO inhibitors, selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and should not be co-administered. Patients with heart disease, glaucoma, impaired liver and kidney function, thyroid dysfunction, or adrenal medullary tumors should use this medication cautiously and must consult a physician before use. During the use of this medication, various side effects such as drowsiness, dizziness, dry mouth, constipation, and visual disturbances may occur; if symptoms worsen, consult a physician immediately. Particularly in the early stages of treatment, psychological changes such as anxiety, restlessness, aggression, and suicidal thoughts may occur, so it is important for family members or caregivers to closely monitor the patient's condition. Pregnant or breastfeeding women should consult their physician before taking this medication, as it may affect the fetus or newborn, warranting caution. This medication is not recommended for children and adolescents due to lack of established safety and efficacy, and elderly patients should be cautious due to reduced drug metabolism, increasing the risk of side effects. In case of overdose, serious cardiac issues or neurological abnormalities may occur, requiring immediate hospital treatment; do not stop taking the medication arbitrarily but gradually reduce the dose as directed by a physician. Finally, keep this medication out of reach of children and be careful not to transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, breathing difficulties accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Drowsiness
• fatigue
• euphoric state
• increased appetite
• dizziness
• tremors
• headache
• loss of sensation in parts
• hallucinations
• anxiety

Store this medication in a sealed container to prevent air from entering, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

Hard capsule filled with white to pale yellow powder; yellow on top and white on the bottom

Package unit

200 capsules/bottle