Medication info

Tyropha Injection (Typropamide Hydrochloride)

Prescription medicationInjectionsIntravenous injectionApproval withdrawn
Ingredient · strength
Tiropramide Hydrochloride›50mg / 1 ampoule
Manufacturer / importer
Daewoong Pharmaceutical Co., Ltd.
Appearance
This medication is a colorless transparent viscous liquid in a brown ampoule for injection.
Packaging
Ampoule - 3 milliliters/ampoule [x50EA]
Approval status
Approval withdrawn

MFDS item code 198900454 · Approved 1989.07.01 · Insurance code 641602481

This product's status changed to Approval withdrawn on 2025.11.28. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Relief of abdominal cramps and pain (e.g., cholelithiasis) and acute spasmodic pain (colic)
Who receives it
Adults
Adult administration
Adults: Inject 50㎎ (3㎖) of tiropramide hydrochloride intramuscularly or intravenously per dose. The dose may be repeated after 1 hour if needed. Adjust the dose appropriately according to age and symptoms.

Ingredients

Manufacturer
Daewoong Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of abdominal cramps and pain (e.g., cholelithiasis) and acute spasmodic pain (colic)

  • Acute spasmodic pain
  • biliary colic
  • abdominal pain
  • renal and ureteric colic
  • abdominal cramps
  • pain
View approved original text

This medication is used to treat acute spasmodic pain such as biliary colic, renal and ureteric colic, as well as gastrointestinal motility disorders, cholelithiasis, cholecystitis, and abdominal cramps and pain due to postoperative adhesions.

How it is given

Adult administration

Adults: Inject 50㎎ (3㎖) of tiropramide hydrochloride intramuscularly or intravenously per dose. The dose may be repeated after 1 hour if needed. Adjust the dose appropriately according to age and symptoms.

Precautions

This medication should not be used in patients with narrowed gastrointestinal tracts, as it may worsen the condition due to obstruction. Additionally, it should not be administered to patients with abnormally distended megacolon or those with dysfunctional bowel. Patients with an allergic reaction to this medication should also avoid its use. It is not safe to administer this drug to patients with severe liver failure. Although this drug does not have anticholinergic effects, it should be used with caution in patients with glaucoma or prostate hyperplasia. Patients with these conditions may experience worsened symptoms from the medication, so it should be administered carefully under a doctor's supervision. Using this medication may lead to symptoms such as dry mouth, nausea, vomiting, or constipation. Additionally, if any allergic reactions, such as itching or red spots on the skin, occur, use should be halted immediately. Caution is necessary for patients taking antihypertensive medications, as excessive use of this drug may lead to excessively low blood pressure. For pregnant women, while no significant issues have been found in animal studies, it should be used restrictively under medical supervision only when necessary. When administered intravenously, it should be injected slowly in patients with low blood pressure. When opening the ampoule, there is a risk of glass fragments entering, so care should be taken, especially when using it for children or the elderly, to avoid contamination with glass.

Side effects

  • dry mouth
  • nausea
  • vomiting
  • constipation
  • itching
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container that blocks light, at a temperature between 1 and 30 degrees Celsius. This ensures that the efficacy of the medication is well maintained and prevents degradation.

Appearance and packaging

Appearance

This medication is a colorless transparent viscous liquid in a brown ampoule for injection.

Package unit

Ampoule - 3 milliliters/ampoule [x50EA]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.